STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TtkTTK protein kinase. (841 aa)    
Predicted Functional Partners:
Ndc80
NDC80 kinetochore complex component.
   
 
 0.996
Mad2l1
Mitotic arrest deficient 2 like 1.
   
 
 0.995
Mad1l1
Mitotic arrest deficient 1 like 1.
    
 0.992
Bub1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 
 0.988
Nuf2
NUF2 component of NDC80 kinetochore complex.
   
 
 0.987
Bub1b
BUB1 mitotic checkpoint serine/threonine kinase B.
   
 
 0.976
Kif11
Kinesin family member 11.
   
 
 0.975
Espl1
Extra spindle pole bodies like 1, separase.
   
 
 0.953
Dlgap5
DLG associated protein 5.
   
  
 0.951
Cenpe
Centromere protein E.
   
  
 0.947
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.