STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Map3k3Mitogen-activated protein kinase kinase kinase 3. (626 aa)    
Predicted Functional Partners:
Map2k5
Mitogen-activated protein kinase kinase 5.
  
0.995
Ccm2
CCM2 scaffold protein.
    
 0.979
Traf6
TNF receptor associated factor 6.
   
 0.963
Pak2
P21 (RAC1) activated kinase 2.
  
 
0.921
Map2k1
Mitogen-activated protein kinase kinase 1.
  
0.920
Map2k2
Mitogen-activated protein kinase kinase 2.
  
0.920
Pak1
P21 (RAC1) activated kinase 1.
    
0.916
Ikbkb
Inhibitor of kappaB kinase beta.
   
0.912
Ikbkg
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
 0.911
Chuk
Component of inhibitor of nuclear factor kappa B kinase complex.
  
0.910
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.