STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSMOCP00000013688annotation not available (88 aa)    
Predicted Functional Partners:
Aph1a
Aph-1 homolog A, gamma-secretase subunit.
   
 0.991
Ncstn
Nicastrin.
    
 0.990
ENSMOCP00000006635
annotation not available
   
 0.990
Psen1
Presenilin 1.
    
 0.990
Psen2
Presenilin 2.
    
 0.990
Notch1
Notch receptor 1.
    
 0.944
Notch2
Notch receptor 2.
    
 0.836
Notch4
Notch receptor 4.
    
 0.836
Notch3
Notch 3.
    
 0.834
App
Amyloid beta precursor protein.
    
 0.828
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.