STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Jak2Janus kinase 2. (1132 aa)    
Predicted Functional Partners:
Stat3
Signal transducer and activator of transcription 3.
   
 0.996
Socs3
Suppressor of cytokine signaling 3.
   
 0.996
Epor
Erythropoietin receptor.
    
 0.995
Socs1
Suppressor of cytokine signaling 1.
   
 0.994
Lepr
Leptin receptor.
    
 0.994
Il6st
Interleukin 6 signal transducer.
   
 0.990
Stat1
Signal transducer and activator of transcription 1.
   
 0.989
Ghr
Growth hormone receptor.
    
 0.986
Csf2rb
Colony stimulating factor 2 receptor beta common subunit.
   
 0.980
Ptpn11
Protein tyrosine phosphatase non-receptor type 11.
   
 0.977
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.