STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Nrde2NRDE-2, necessary for RNA interference, domain containing. (1155 aa)    
Predicted Functional Partners:
Mtrex
Mtr4 exosome RNA helicase.
    
 
 0.969
Plk2
Polo like kinase 2.
    
 0.934
Plk5
Polo like kinase 5.
    
 0.934
Plk1
Polo like kinase 1.
    
 0.934
Plk3
Polo like kinase 3.
    
 0.934
Ppp2r2b
Protein phosphatase 2 regulatory subunit Bbeta.
    
 
 0.931
Ppp2r2a
Protein phosphatase 2 regulatory subunit Balpha.
    
 
 0.931
Plk4
Polo like kinase 4.
    
 0.921
Tbc1d2b
TBC1 domain family member 2B.
    
 0.892
Tbc1d2
TBC1 domain family member 2.
    
 0.892
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.