STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Zc3h12dZinc finger CCCH-type containing 12D. (531 aa)    
Predicted Functional Partners:
Il12rb1
Interleukin 12 receptor subunit beta 1.
   
    0.765
Ikbkg
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
  0.709
Optn
Optineurin.
    
  0.668
Casp8
Caspase 8.
     
 0.615
Tank
TRAF family member associated NFKB activator.
   
 
 0.486
ENSMOCP00000008369
annotation not available
    
   0.463
Nedd8
NEDD8 ubiquitin like modifier.
    
   0.463
LOC101997722
NEDD8.
    
   0.463
Foxa1
Forkhead box A1.
    
  0.459
Foxa2
Forkhead box A2.
    
  0.459
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.