STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Srebf1Sterol regulatory element binding transcription factor 1. (1130 aa)    
Predicted Functional Partners:
Scap
SREBF chaperone.
   
 0.986
Npc1
NPC intracellular cholesterol transporter 1.
   
 0.946
Npc1l1
NPC1 like intracellular cholesterol transporter 1.
   
 0.946
Fbxw7
F-box and WD repeat domain containing 7.
    
 0.927
Kpnb1
Karyopherin subunit beta 1.
    
 0.920
Ppargc1b
PPARG coactivator 1 beta.
    
 0.918
Ep300
E1A binding protein p300.
    
 0.899
Crebbp
CREB binding protein.
    
 0.866
Med15
Mediator complex subunit 15.
    
 
 0.843
Lmna
Lamin A/C.
    
 
 0.834
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.