STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Nsmce2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (247 aa)    
Predicted Functional Partners:
Smc6
Structural maintenance of chromosomes 6.
    
 0.999
Nsmce4a
NSE4 homolog A, SMC5-SMC6 complex component.
    
 0.999
Smc5
Structural maintenance of chromosomes 5.
    
 0.999
Nsmce1
NSE1 homolog, SMC5-SMC6 complex component.
    
 0.999
Nsmce3
NSE3 homolog, SMC5-SMC6 complex component.
    
 0.972
Smc3
Structural maintenance of chromosomes 3.
    
 0.968
Smc2
Structural maintenance of chromosomes 2.
    
 0.958
Smc1b
Structural maintenance of chromosomes 1B.
    
 0.956
Smc1a
Structural maintenance of chromosomes 1A.
    
 0.956
Smc4
Structural maintenance of chromosomes 4.
    
 0.951
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.