STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Irf8Interferon regulatory factor 8. (424 aa)    
Predicted Functional Partners:
Irf1
Interferon regulatory factor 1.
   
0.882
Traf6
TNF receptor associated factor 6.
   
 0.847
Spi1
Spi-1 proto-oncogene.
   
 
 0.834
Spib
Spi-B transcription factor.
   
 
 0.758
Sgk3
Serine/threonine-protein kinase Sgk3.
    
 0.752
Suox
Sulfite oxidase.
     
 0.750
Ep300
E1A binding protein p300.
    
 0.724
Crebbp
CREB binding protein.
    
 0.707
Cenpp
Centromere protein P.
    
 0.697
Dusp15
Dual specificity phosphatase 15.
 
  
 0.696
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.