STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Plekha1Pleckstrin homology domain containing A1. (383 aa)    
Predicted Functional Partners:
Rint1
RAD50 interactor 1.
    
 0.911
Use1
Unconventional SNARE in the ER 1.
    
 0.897
Stx18
Syntaxin 18.
    
 0.896
Zw10
Zw10 kinetochore protein.
    
 0.883
Nbas
NBAS subunit of NRZ tethering complex.
    
 0.865
Sec22a
SEC22 homolog A, vesicle trafficking protein.
   
 0.763
Sec22c
SEC22 homolog C, vesicle trafficking protein.
   
 0.763
Sec22b
SEC22 homolog B, vesicle trafficking protein.
   
 0.763
Tsc2
TSC complex subunit 2.
    
 0.697
Nsf
N-ethylmaleimide sensitive factor, vesicle fusing ATPase.
    
 0.692
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.