STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sh3pxd2aSH3 and PX domains 2A. (1124 aa)    
Predicted Functional Partners:
Adam15
ADAM metallopeptidase domain 15.
    
 0.813
Adam12
A disintegrin and metallopeptidase domain 12 (meltrin alpha).
    
 0.794
Cdc42
Cell division cycle 42.
    
 0.779
Adam19
ADAM metallopeptidase domain 19.
    
 0.772
Noxa1
NADPH oxidase activator 1.
    
 0.766
Pak4
P21 (RAC1) activated kinase 4.
    
 0.759
Pak1
P21 (RAC1) activated kinase 1.
    
 0.759
Pak3
P21 (RAC1) activated kinase 3.
    
 0.759
Pak7
P21 (RAC1) activated kinase 5.
    
 0.759
Pak2
P21 (RAC1) activated kinase 2.
    
 0.759
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.