STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sp1Sp1 transcription factor. (786 aa)    
Predicted Functional Partners:
Esr1
Estrogen receptor 1.
    
 0.994
Ep300
E1A binding protein p300.
   
 0.994
Crebbp
CREB binding protein.
   
 0.984
Jun
Jun proto-oncogene, AP-1 transcription factor subunit.
   
 0.980
Esr2
Estrogen receptor 2.
    
 0.969
Trp53
Tumor protein p53.
    
 0.964
Smad3
SMAD family member 3.
    
 0.961
Tbp
TATA-box binding protein.
    
 0.950
Hdac1
Histone deacetylase 1.
    
 0.948
ENSMOCP00000016007
annotation not available
    
 0.948
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.