STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BcrBCR activator of RhoGEF and GTPase. (1064 aa)    
Predicted Functional Partners:
Grb2
Growth factor receptor bound protein 2.
    
 0.987
Cbl
Cbl proto-oncogene.
    
  0.926
Crkl
CRK like proto-oncogene, adaptor protein.
    
 0.919
Crk
CRK proto-oncogene, adaptor protein.
    
 0.899
Abl2
ABL proto-oncogene 2, non-receptor tyrosine kinase.
    
 0.897
ENSMOCP00000006837
annotation not available
    
 0.897
Shc3
Src homology 2 domain-containing transforming protein C3.
    
  0.844
Stat5b
Signal transducer and activator of transcription 5B.
     
 0.841
Stat5a
Signal transducer and activator of transcription 5A.
     
 0.833
Grap2
GRB2 related adaptor protein 2.
    
 0.821
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.