STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HprtHypoxanthine phosphoribosyltransferase 1. (218 aa)    
Predicted Functional Partners:
Adsl
Adenylosuccinate lyase.
    
 0.921
Aprt
Adenine phosphoribosyltransferase.
   
 0.915
Mtap
Methylthioadenosine phosphorylase.
  
 0.914
Pnp
Purine nucleoside phosphorylase.
  
 0.908
Gmps
Guanine monophosphate synthase.
  
 
 0.907
Atic
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.
    
 0.906
Rrm1
Ribonucleotide reductase catalytic subunit M1.
  
 
 0.901
Adss
Adenylosuccinate synthase 2.
  
 
 0.898
Gart
annotation not available
  
 
 0.896
Wdr90
WD repeat domain 90.
    
   0.884
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.