STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NrasNRAS proto-oncogene, GTPase. (189 aa)    
Predicted Functional Partners:
Pik3ca
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
   
 0.985
Pik3cg
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma.
    
 0.983
Pik3cd
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta.
    
 0.983
Nf1
Neurofibromin 1.
    
 0.967
Itsn2
Intersectin 2.
    
 0.963
Rgl1
Ral guanine nucleotide dissociation stimulator like 1.
    
 0.957
Plce1
Phospholipase C, epsilon 1.
    
 0.956
Sos1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.956
Ralgds
Ral guanine nucleotide dissociation stimulator.
    
 0.956
Raf1
Raf-1 proto-oncogene, serine/threonine kinase.
  
 0.953
Your Current Organism:
Microtus ochrogaster
NCBI taxonomy Id: 79684
Other names: M. ochrogaster, prairie vole, prairie voles
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.