Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
A0A137PBY7Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (794 aa)    
Predicted Functional Partners:
A0A137NXH3
Ribonucleotide reductase.
  
 0.999
A0A137PGD2
Thymidylate synthase.
  
 
 0.953
A0A137PD86
Pkinase-domain-containing protein.
   
 
 0.942
A0A137P8A4
DNA helicase; Belongs to the MCM family.
   
 
 0.941
A0A137NRA4
DNA helicase; Belongs to the MCM family.
   
 
 0.936
A0A137PIT2
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 
 0.928
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
   
 
 0.922
A0A137NQQ6
DNA helicase.
   
  
 0.909
A0A137P1J5
Deoxythymidylate kinase-like protein.
  
 
 0.898
A0A137P533
dUTP pyrophosphatase.
  
 
 0.871
Your Current Organism:
Conidiobolus coronatus
NCBI taxonomy Id: 796925
Other names: C. coronatus NRRL 28638, Conidiobolus coronatus NRRL 28638
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.