STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A137PHS3Thimet oligopeptidase 1. (685 aa)    
Predicted Functional Partners:
A0A137PGF7
Calmodulin mutant SYNCAM35.
 
  
 
 0.862
A0A137NY19
N-acetyl-gamma-glutamyl-phosphate reductase and acetylglutamate kinase; In the N-terminal section; belongs to the acetylglutamate kinase family.
      
 0.539
A0A137NQR6
Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation.
 
      0.521
MCM7
DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]
      
 0.499
A0A137PFL6
BRO1-domain-containing protein.
    
 
 0.481
A0A137NPW5
Creatinase/prolidase N-terminal domain-containing protein.
   
 
 0.449
A0A137PEM3
Uncharacterized protein.
    
 
 0.443
A0A137P2Q0
Putative 10 kDa chaperonin; Belongs to the GroES chaperonin family.
  
 
 0.441
PIM1
Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family.
   
 
 0.433
A0A137PCS2
Frataxin.
   
 
 0.407
Your Current Organism:
Conidiobolus coronatus
NCBI taxonomy Id: 796925
Other names: C. coronatus NRRL 28638, Conidiobolus coronatus NRRL 28638
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.