node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHL15283.1 | aroK | HMPREF9630_00652 | HMPREF9630_01141 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Shikimate 5-dehydrogenase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.509 |
EHL15283.1 | nadD | HMPREF9630_00652 | HMPREF9630_00658 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.841 |
EHL15288.1 | EHL17975.1 | HMPREF9630_00657 | HMPREF9630_01231 | Hypothetical protein. | Hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.852 |
EHL15288.1 | aroK | HMPREF9630_00657 | HMPREF9630_01141 | Hypothetical protein. | Shikimate 5-dehydrogenase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.746 |
EHL15288.1 | cinA | HMPREF9630_00657 | HMPREF9630_00873 | Hypothetical protein. | Competence/damage-inducible protein CinA domain; Belongs to the CinA family. | 0.909 |
EHL15288.1 | nadD | HMPREF9630_00657 | HMPREF9630_00658 | Hypothetical protein. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.997 |
EHL15288.1 | nadE | HMPREF9630_00657 | HMPREF9630_01369 | Hypothetical protein. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.557 |
EHL15288.1 | nadK | HMPREF9630_00657 | HMPREF9630_00798 | Hypothetical protein. | Hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.784 |
EHL15288.1 | rsfS | HMPREF9630_00657 | HMPREF9630_00655 | Hypothetical protein. | Iojap-like ribosome-associated protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.921 |
EHL16337.1 | EHL17975.1 | HMPREF9630_01909 | HMPREF9630_01231 | Hypothetical protein. | Hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.731 |
EHL16337.1 | cinA | HMPREF9630_01909 | HMPREF9630_00873 | Hypothetical protein. | Competence/damage-inducible protein CinA domain; Belongs to the CinA family. | 0.905 |
EHL16337.1 | nadD | HMPREF9630_01909 | HMPREF9630_00658 | Hypothetical protein. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.746 |
EHL16337.1 | nadE | HMPREF9630_01909 | HMPREF9630_01369 | Hypothetical protein. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.431 |
EHL17975.1 | EHL15288.1 | HMPREF9630_01231 | HMPREF9630_00657 | Hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Hypothetical protein. | 0.852 |
EHL17975.1 | EHL16337.1 | HMPREF9630_01231 | HMPREF9630_01909 | Hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Hypothetical protein. | 0.731 |
EHL17975.1 | cinA | HMPREF9630_01231 | HMPREF9630_00873 | Hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Competence/damage-inducible protein CinA domain; Belongs to the CinA family. | 0.970 |
EHL17975.1 | cobB | HMPREF9630_01231 | HMPREF9630_00487 | Hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Hypothetical protein; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class U subfamily. | 0.639 |
EHL17975.1 | nadD | HMPREF9630_01231 | HMPREF9630_00658 | Hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.963 |
EHL17975.1 | nadE | HMPREF9630_01231 | HMPREF9630_01369 | Hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.792 |
EHL17975.1 | nadK | HMPREF9630_01231 | HMPREF9630_00798 | Hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Hypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.457 |