EHL17570.1 protein (Peptoanaerobacter stomatis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

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[Homology]

Score

EHL17570.1

Hypothetical protein. (87 aa)

Predicted Functional Partners:

EHL17571.2

0.995

EHL17573.1

0.992

EHL17581.1

0.985

EHL17577.1

0.966

EHL17569.1

0.926

EHL17574.1

0.811

EHL17562.1

0.792

EHL17567.1

0.760

EHL17563.1

0.737

EHL17568.1

0.717

Your Current Organism:

Peptoanaerobacter stomatis

NCBI taxonomy Id: 796937
Other names: ATCC BAA-2665, DSM 28705, HM-483, P. stomatis, Peptoanaerobacter stomatis Sizova et al. 2016, Peptostreptococcaceae bacterium ACC19a, Peptostreptococcaceae bacterium CM2, Peptostreptococcaceae bacterium CM5, Peptostreptococcaceae bacterium OBRC8, strain ACC19a

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EHL17562.1	EHL17563.1	HMPREF9630_01574	HMPREF9630_01575	Hypothetical protein.	Hypothetical protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.	0.981
EHL17562.1	EHL17567.1	HMPREF9630_01574	HMPREF9630_01579	Hypothetical protein.	Hypothetical protein.	0.687
EHL17562.1	EHL17568.1	HMPREF9630_01574	HMPREF9630_01580	Hypothetical protein.	Hypothetical protein.	0.985
EHL17562.1	EHL17569.1	HMPREF9630_01574	HMPREF9630_01581	Hypothetical protein.	Hypothetical protein.	0.828
EHL17562.1	EHL17570.1	HMPREF9630_01574	HMPREF9630_01582	Hypothetical protein.	Hypothetical protein.	0.792
EHL17562.1	EHL17571.2	HMPREF9630_01574	HMPREF9630_01583	Hypothetical protein.	Hypothetical protein.	0.816
EHL17562.1	EHL17573.1	HMPREF9630_01574	HMPREF9630_01585	Hypothetical protein.	Propanediol utilization protein PduA.	0.808
EHL17562.1	EHL17574.1	HMPREF9630_01574	HMPREF9630_01586	Hypothetical protein.	Hypothetical protein.	0.836
EHL17562.1	EHL17577.1	HMPREF9630_01574	HMPREF9630_01589	Hypothetical protein.	Hypothetical protein.	0.582
EHL17562.1	EHL17581.1	HMPREF9630_01574	HMPREF9630_01593	Hypothetical protein.	Hypothetical protein.	0.700
EHL17563.1	EHL17562.1	HMPREF9630_01575	HMPREF9630_01574	Hypothetical protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.	Hypothetical protein.	0.981
EHL17563.1	EHL17567.1	HMPREF9630_01575	HMPREF9630_01579	Hypothetical protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.	Hypothetical protein.	0.640
EHL17563.1	EHL17568.1	HMPREF9630_01575	HMPREF9630_01580	Hypothetical protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.	Hypothetical protein.	0.684
EHL17563.1	EHL17569.1	HMPREF9630_01575	HMPREF9630_01581	Hypothetical protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.	Hypothetical protein.	0.891
EHL17563.1	EHL17570.1	HMPREF9630_01575	HMPREF9630_01582	Hypothetical protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.	Hypothetical protein.	0.737
EHL17563.1	EHL17571.2	HMPREF9630_01575	HMPREF9630_01583	Hypothetical protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.	Hypothetical protein.	0.800
EHL17563.1	EHL17573.1	HMPREF9630_01575	HMPREF9630_01585	Hypothetical protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.	Propanediol utilization protein PduA.	0.754
EHL17563.1	EHL17574.1	HMPREF9630_01575	HMPREF9630_01586	Hypothetical protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.	Hypothetical protein.	0.616
EHL17563.1	EHL17581.1	HMPREF9630_01575	HMPREF9630_01593	Hypothetical protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.	Hypothetical protein.	0.500
EHL17567.1	EHL17562.1	HMPREF9630_01579	HMPREF9630_01574	Hypothetical protein.	Hypothetical protein.	0.687

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

18

average node degree:

3.27

avg. local clustering coefficient:

0.865

expected number of edges:

14

PPI enrichment p-value:

0.155

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015031

Protein transport

7 of 112

1.58

2.43

1.15e-07

GO:0006810

Transport

10 of 524

1.07

1.31

1.15e-07

GO:0055085

Transmembrane transport

5 of 402

0.88

0.53

0.0253

GO:0009987

Cellular process

11 of 2988

0.35

0.28

0.0139

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0060089

Molecular transducer activity

3 of 20

1.96

1.24

0.0038

GO:0022857

Transmembrane transporter activity

6 of 329

1.05

0.79

0.0038

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016021

Integral component of membrane

10 of 994

0.79

0.77

6.98e-06

GO:0005886

Plasma membrane

7 of 597

0.85

0.74

0.00038

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5456

Mixed, incl. Protein transport, and TonB/TolA, C-terminal

7 of 28

2.18

4.82

2.57e-11

CL:5457

Mixed, incl. Protein transport, and Protein of unknown function DUF421

6 of 23

2.2

4.2

1.22e-09

CL:5458

Mixed, incl. Protein transport, and Protein of unknown function DUF421

5 of 16

2.28

3.72

2.93e-08

CL:5462

Biopolymer transport protein ExbD/TolR, and Outer membrane lipoprotein BamD-like

4 of 5

2.69

3.7

1.17e-07

CL:7092

Mixed, incl. TonB/TolA, C-terminal, and Putative porin

2 of 6

2.31

1.04

0.0122

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005886

Plasma membrane

6 of 422

0.94

0.67

0.0062

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0653

Protein transport

7 of 23

2.27

5.51

1.14e-12

KW-0812

Transmembrane

9 of 1256

0.64

0.52

0.00077

KW-1133

Transmembrane helix

8 of 1247

0.59

0.43

0.0059

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01618

MotA/TolQ/ExbB proton channel family

5 of 8

2.58

4.39

3.73e-09

PF02472

Biopolymer transport protein ExbD/TolR

2 of 7

2.24

0.82

0.0315

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR002898

MotA/TolQ/ExbB proton channel

5 of 8

2.58

4.2

9.12e-09

IPR006260

TonB/TolA, C-terminal

2 of 2

2.79

1.04

0.0129

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