node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHO16600.1 | EHO17440.1 | HMPREF9623_01299 | HMPREF9623_01039 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Hypothetical protein. | 0.783 |
EHO16600.1 | EHO17528.1 | HMPREF9623_01299 | HMPREF9623_01127 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.515 |
EHO16600.1 | EHO18130.1 | HMPREF9623_01299 | HMPREF9623_00314 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | Hypothetical protein. | 0.733 |
EHO17440.1 | EHO16600.1 | HMPREF9623_01039 | HMPREF9623_01299 | Hypothetical protein. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.783 |
EHO17440.1 | EHO18130.1 | HMPREF9623_01039 | HMPREF9623_00314 | Hypothetical protein. | Hypothetical protein. | 0.649 |
EHO17528.1 | EHO16600.1 | HMPREF9623_01127 | HMPREF9623_01299 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.515 |
EHO17528.1 | EHO18130.1 | HMPREF9623_01127 | HMPREF9623_00314 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Hypothetical protein. | 0.910 |
EHO17528.1 | EHO18133.1 | HMPREF9623_01127 | HMPREF9623_00317 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Hypothetical protein; Belongs to the SEDS family. | 0.411 |
EHO18124.1 | EHO18127.1 | HMPREF9623_00308 | HMPREF9623_00311 | RluA family pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | 0.740 |
EHO18124.1 | EHO18128.1 | HMPREF9623_00308 | HMPREF9623_00312 | RluA family pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.813 |
EHO18124.1 | EHO18129.1 | HMPREF9623_00308 | HMPREF9623_00313 | RluA family pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Hypothetical protein. | 0.809 |
EHO18124.1 | EHO18130.1 | HMPREF9623_00308 | HMPREF9623_00314 | RluA family pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Hypothetical protein. | 0.593 |
EHO18124.1 | EHO18131.1 | HMPREF9623_00308 | HMPREF9623_00315 | RluA family pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Hypothetical protein; Belongs to the peptidase S11 family. | 0.408 |
EHO18124.1 | mgsA | HMPREF9623_00308 | HMPREF9623_00316 | RluA family pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. | 0.448 |
EHO18127.1 | EHO18124.1 | HMPREF9623_00311 | HMPREF9623_00308 | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | RluA family pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.740 |
EHO18127.1 | EHO18128.1 | HMPREF9623_00311 | HMPREF9623_00312 | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family. | 0.957 |
EHO18127.1 | EHO18129.1 | HMPREF9623_00311 | HMPREF9623_00313 | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | Hypothetical protein. | 0.827 |
EHO18127.1 | EHO18130.1 | HMPREF9623_00311 | HMPREF9623_00314 | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | Hypothetical protein. | 0.667 |
EHO18127.1 | EHO18131.1 | HMPREF9623_00311 | HMPREF9623_00315 | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | Hypothetical protein; Belongs to the peptidase S11 family. | 0.436 |
EHO18127.1 | EHO18133.1 | HMPREF9623_00311 | HMPREF9623_00317 | Hypothetical protein; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. | Hypothetical protein; Belongs to the SEDS family. | 0.478 |