node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
clpP | rpsG | HMPREF9623_00615 | HMPREF9623_01195 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.421 |
clpP | rpsK | HMPREF9623_00615 | HMPREF9623_00786 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.464 |
clpP | tig | HMPREF9623_00615 | HMPREF9623_00616 | ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.901 |
rplC | rplD | HMPREF9623_00812 | HMPREF9623_00811 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.999 |
rplC | rplQ | HMPREF9623_00812 | HMPREF9623_00783 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 50S ribosomal protein L17. | 0.996 |
rplC | rplW | HMPREF9623_00812 | HMPREF9623_00810 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.999 |
rplC | rpsB | HMPREF9623_00812 | HMPREF9623_01902 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.995 |
rplC | rpsG | HMPREF9623_00812 | HMPREF9623_01195 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.997 |
rplC | rpsI | HMPREF9623_00812 | HMPREF9623_00445 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.996 |
rplC | rpsK | HMPREF9623_00812 | HMPREF9623_00786 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.998 |
rplC | rpsU | HMPREF9623_00812 | HMPREF9623_00333 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 30S ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. | 0.957 |
rplC | tig | HMPREF9623_00812 | HMPREF9623_00616 | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.901 |
rplD | rplC | HMPREF9623_00811 | HMPREF9623_00812 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.999 |
rplD | rplQ | HMPREF9623_00811 | HMPREF9623_00783 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 50S ribosomal protein L17. | 0.996 |
rplD | rplW | HMPREF9623_00811 | HMPREF9623_00810 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. | 0.999 |
rplD | rpsB | HMPREF9623_00811 | HMPREF9623_01902 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 30S ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.999 |
rplD | rpsG | HMPREF9623_00811 | HMPREF9623_01195 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.999 |
rplD | rpsI | HMPREF9623_00811 | HMPREF9623_00445 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.996 |
rplD | rpsK | HMPREF9623_00811 | HMPREF9623_00786 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.999 |
rplD | rpsU | HMPREF9623_00811 | HMPREF9623_00333 | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 30S ribosomal protein S21; Belongs to the bacterial ribosomal protein bS21 family. | 0.955 |