EHO17328.1 protein (Stomatobaculum longum) - STRING interaction network

Nodes:

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

EHO17328.1

Hypothetical protein. (314 aa)

Predicted Functional Partners:

pxpA

0.999

EHO17327.1

0.999

EHO17326.1

0.922

EHO17329.1

0.856

EHO17090.1

0.767

EHO16730.1

0.664

EHO16057.1

0.605

EHO17235.1

0.499

EHO18039.1

0.491

EHO18219.1

0.450

Your Current Organism:

Stomatobaculum longum

NCBI taxonomy Id: 796942
Other names: DSM 24645, Lachnospiraceae bacterium ACC2, S. longum, Stomatobaculum longum Sizova et al. 2013, strain ACC2, strain HM-480

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EHO16057.1	EHO16730.1	HMPREF9623_01603	HMPREF9623_01429	Hypothetical protein; Belongs to the D-glutamate cyclase family.	Hypothetical protein.	0.444
EHO16057.1	EHO17326.1	HMPREF9623_01603	HMPREF9623_00925	Hypothetical protein; Belongs to the D-glutamate cyclase family.	Hypothetical protein.	0.879
EHO16057.1	EHO17327.1	HMPREF9623_01603	HMPREF9623_00926	Hypothetical protein; Belongs to the D-glutamate cyclase family.	TIGR00370 family protein.	0.663
EHO16057.1	EHO17328.1	HMPREF9623_01603	HMPREF9623_00927	Hypothetical protein; Belongs to the D-glutamate cyclase family.	Hypothetical protein.	0.605
EHO16057.1	pxpA	HMPREF9623_01603	HMPREF9623_00924	Hypothetical protein; Belongs to the D-glutamate cyclase family.	Hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.	0.594
EHO16730.1	EHO16057.1	HMPREF9623_01429	HMPREF9623_01603	Hypothetical protein.	Hypothetical protein; Belongs to the D-glutamate cyclase family.	0.444
EHO16730.1	EHO17235.1	HMPREF9623_01429	HMPREF9623_00834	Hypothetical protein.	Hypothetical protein.	0.466
EHO16730.1	EHO17326.1	HMPREF9623_01429	HMPREF9623_00925	Hypothetical protein.	Hypothetical protein.	0.459
EHO16730.1	EHO17327.1	HMPREF9623_01429	HMPREF9623_00926	Hypothetical protein.	TIGR00370 family protein.	0.713
EHO16730.1	EHO17328.1	HMPREF9623_01429	HMPREF9623_00927	Hypothetical protein.	Hypothetical protein.	0.664
EHO16730.1	EHO17329.1	HMPREF9623_01429	HMPREF9623_00928	Hypothetical protein.	Hypothetical protein; Belongs to the D-glutamate cyclase family.	0.444
EHO16730.1	pxpA	HMPREF9623_01429	HMPREF9623_00924	Hypothetical protein.	Hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.	0.459
EHO17090.1	EHO17235.1	HMPREF9623_00689	HMPREF9623_00834	NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Hypothetical protein.	0.528
EHO17090.1	EHO17327.1	HMPREF9623_00689	HMPREF9623_00926	NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	TIGR00370 family protein.	0.447
EHO17090.1	EHO17328.1	HMPREF9623_00689	HMPREF9623_00927	NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Hypothetical protein.	0.767
EHO17090.1	EHO18039.1	HMPREF9623_00689	HMPREF9623_00223	NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Hypothetical protein.	0.485
EHO17090.1	EHO18219.1	HMPREF9623_00689	HMPREF9623_00403	NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Hypothetical protein; Belongs to the aldehyde dehydrogenase family.	0.819
EHO17235.1	EHO16730.1	HMPREF9623_00834	HMPREF9623_01429	Hypothetical protein.	Hypothetical protein.	0.466
EHO17235.1	EHO17090.1	HMPREF9623_00834	HMPREF9623_00689	Hypothetical protein.	NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.528
EHO17235.1	EHO17327.1	HMPREF9623_00834	HMPREF9623_00926	Hypothetical protein.	TIGR00370 family protein.	0.520

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Network Stats

number of nodes:

11

number of edges:

51

average node degree:

9.27

avg. local clustering coefficient:

0.941

expected number of edges:

16

PPI enrichment p-value:

2.03e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006796

Phosphate-containing compound metabolic process

9 of 236

1.01

1.17

2.57e-07

GO:0044271

Cellular nitrogen compound biosynthetic process

9 of 327

0.86

0.88

3.63e-06

GO:1901566

Organonitrogen compound biosynthetic process

9 of 407

0.77

0.72

2.10e-05

GO:0006139

Nucleobase-containing compound metabolic process

9 of 537

0.65

0.55

0.00022

GO:0034641

Cellular nitrogen compound metabolic process

10 of 707

0.57

0.49

0.00014

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0046933

Proton-transporting ATP synthase activity, rotational mechanism

8 of 9

2.37

6.45

1.76e-14

GO:0046961

Proton-transporting ATPase activity, rotational mechanism

2 of 3

2.25

1.23

0.0050

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0045259

Proton-transporting ATP synthase complex

8 of 9

2.37

6.71

3.72e-15

GO:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

5 of 6

2.34

4.18

3.68e-09

GO:0045263

Proton-transporting ATP synthase complex, coupling factor F(o)

3 of 3

2.42

2.56

1.40e-05

GO:0005886

Plasma membrane

8 of 491

0.64

0.51

0.00095

GO:0005622

Intracellular anatomical structure

10 of 1040

0.41

0.33

0.0029

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:22479625

(2012) Comparative analysis of gene content evolution in phytoplasmas and mycoplasmas.

4 of 102

1.02

0.56

0.0355

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:249

ATP synthesis

8 of 8

2.42

6.65

1.05e-14

CL:84

Ribosome, and Ribonucleoside triphosphate biosynthetic process

10 of 91

1.46

2.77

5.39e-12

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pth00190

Oxidative phosphorylation

9 of 19

2.1

6.04

8.55e-16

pth01100

Metabolic pathways

8 of 503

0.63

0.47

0.0041

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0045259

Proton-transporting ATP synthase complex

8 of 10

2.33

6.39

1.27e-14

GOCC:0045261

Proton-transporting ATP synthase complex, catalytic core F(1)

5 of 5

2.42

4.26

3.81e-09

GOCC:0045263

Proton-transporting ATP synthase complex, coupling factor F(o)

3 of 5

2.2

2.13

7.39e-05

GOCC:0032991

Protein-containing complex

9 of 435

0.74

0.67

6.39e-05

GOCC:0005622

Intracellular

10 of 995

0.43

0.34

0.0039

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0375

Hydrogen ion transport

8 of 8

2.42

6.87

3.09e-15

KW-0066

ATP synthesis

8 of 8

2.42

6.87

3.09e-15

KW-0139

CF(1)

5 of 5

2.42

4.29

3.15e-09

KW-0138

CF(0)

3 of 3

2.42

2.46

2.19e-05

KW-1003

Cell membrane

8 of 110

1.29

1.85

2.66e-08

(more ...)

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