node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHO15924.1 | EHO16108.1 | HMPREF9623_01835 | HMPREF9623_01654 | Pyruvate kinase; Belongs to the pyruvate kinase family. | PTS system, glucose subfamily, IIA component. | 0.847 |
EHO15924.1 | EHO16535.1 | HMPREF9623_01835 | HMPREF9623_01234 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.876 |
EHO15924.1 | EHO18580.1 | HMPREF9623_01835 | HMPREF9623_00048 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.997 |
EHO15924.1 | eno | HMPREF9623_01835 | HMPREF9623_01804 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.994 |
EHO15924.1 | pfkA | HMPREF9623_01835 | HMPREF9623_01677 | Pyruvate kinase; Belongs to the pyruvate kinase family. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.789 |
EHO15924.1 | pfkA-2 | HMPREF9623_01835 | HMPREF9623_02046 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Hypothetical protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. | 0.787 |
EHO15924.1 | pfp | HMPREF9623_01835 | HMPREF9623_01818 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Hypothetical protein; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.695 |
EHO15924.1 | pgi | HMPREF9623_01835 | HMPREF9623_01083 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Hypothetical protein; Belongs to the GPI family. | 0.989 |
EHO15924.1 | pgk | HMPREF9623_01835 | HMPREF9623_01235 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Hypothetical protein; Belongs to the phosphoglycerate kinase family. | 0.904 |
EHO15924.1 | tpiA | HMPREF9623_01835 | HMPREF9623_01236 | Pyruvate kinase; Belongs to the pyruvate kinase family. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.890 |
EHO16108.1 | EHO15924.1 | HMPREF9623_01654 | HMPREF9623_01835 | PTS system, glucose subfamily, IIA component. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.847 |
EHO16108.1 | EHO16535.1 | HMPREF9623_01654 | HMPREF9623_01234 | PTS system, glucose subfamily, IIA component. | Glyceraldehyde-3-phosphate dehydrogenase, type I; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.750 |
EHO16108.1 | EHO18580.1 | HMPREF9623_01654 | HMPREF9623_00048 | PTS system, glucose subfamily, IIA component. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.926 |
EHO16108.1 | eno | HMPREF9623_01654 | HMPREF9623_01804 | PTS system, glucose subfamily, IIA component. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | 0.762 |
EHO16108.1 | pfkA | HMPREF9623_01654 | HMPREF9623_01677 | PTS system, glucose subfamily, IIA component. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.538 |
EHO16108.1 | pfkA-2 | HMPREF9623_01654 | HMPREF9623_02046 | PTS system, glucose subfamily, IIA component. | Hypothetical protein; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. | 0.538 |
EHO16108.1 | pfp | HMPREF9623_01654 | HMPREF9623_01818 | PTS system, glucose subfamily, IIA component. | Hypothetical protein; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.538 |
EHO16108.1 | pgi | HMPREF9623_01654 | HMPREF9623_01083 | PTS system, glucose subfamily, IIA component. | Hypothetical protein; Belongs to the GPI family. | 0.984 |
EHO16108.1 | pgk | HMPREF9623_01654 | HMPREF9623_01235 | PTS system, glucose subfamily, IIA component. | Hypothetical protein; Belongs to the phosphoglycerate kinase family. | 0.746 |
EHO16108.1 | tpiA | HMPREF9623_01654 | HMPREF9623_01236 | PTS system, glucose subfamily, IIA component. | Triose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.769 |