scpA protein (Stomatobaculum longum) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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scpA

Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. (266 aa)

Predicted Functional Partners:

EHO17715.1

0.999

smc

0.984

EHO15890.1

0.840

EHO15889.1

0.787

EHO18022.1

0.723

EHO17158.1

0.723

EHO16558.1

0.723

EHO15707.1

0.723

EHO17518.1

0.717

cmk

0.697

Your Current Organism:

Stomatobaculum longum

NCBI taxonomy Id: 796942
Other names: DSM 24645, Lachnospiraceae bacterium ACC2, S. longum, Stomatobaculum longum Sizova et al. 2013, strain ACC2, strain HM-480

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EHO15707.1	scpA	HMPREF9623_02028	HMPREF9623_01802	Hypothetical protein.	Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.	0.723
EHO15889.1	EHO15890.1	HMPREF9623_01800	HMPREF9623_01801	Hypothetical protein; Belongs to the peptidase S11 family.	Hypothetical protein.	0.775
EHO15889.1	scpA	HMPREF9623_01800	HMPREF9623_01802	Hypothetical protein; Belongs to the peptidase S11 family.	Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.	0.787
EHO15890.1	EHO15889.1	HMPREF9623_01801	HMPREF9623_01800	Hypothetical protein.	Hypothetical protein; Belongs to the peptidase S11 family.	0.775
EHO15890.1	scpA	HMPREF9623_01801	HMPREF9623_01802	Hypothetical protein.	Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.	0.840
EHO16558.1	scpA	HMPREF9623_01257	HMPREF9623_01802	Hypothetical protein.	Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.	0.723
EHO17158.1	scpA	HMPREF9623_00757	HMPREF9623_01802	Hypothetical protein.	Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.	0.723
EHO17518.1	scpA	HMPREF9623_01117	HMPREF9623_01802	Hypothetical protein.	Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.	0.717
EHO17715.1	cmk	HMPREF9623_00569	HMPREF9623_00546	Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.	Cytidylate kinase.	0.974
EHO17715.1	scpA	HMPREF9623_00569	HMPREF9623_01802	Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.	Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.	0.999
EHO17715.1	smc	HMPREF9623_00569	HMPREF9623_00087	Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.	Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.	0.839
EHO18022.1	scpA	HMPREF9623_00206	HMPREF9623_01802	Hypothetical protein.	Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.	0.723
cmk	EHO17715.1	HMPREF9623_00546	HMPREF9623_00569	Cytidylate kinase.	Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.	0.974
cmk	scpA	HMPREF9623_00546	HMPREF9623_01802	Cytidylate kinase.	Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.	0.697
scpA	EHO15707.1	HMPREF9623_01802	HMPREF9623_02028	Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.	Hypothetical protein.	0.723
scpA	EHO15889.1	HMPREF9623_01802	HMPREF9623_01800	Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.	Hypothetical protein; Belongs to the peptidase S11 family.	0.787
scpA	EHO15890.1	HMPREF9623_01802	HMPREF9623_01801	Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.	Hypothetical protein.	0.840
scpA	EHO16558.1	HMPREF9623_01802	HMPREF9623_01257	Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.	Hypothetical protein.	0.723
scpA	EHO17158.1	HMPREF9623_01802	HMPREF9623_00757	Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.	Hypothetical protein.	0.723
scpA	EHO17518.1	HMPREF9623_01802	HMPREF9623_01117	Hypothetical protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.	Hypothetical protein.	0.717

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Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

11

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

7 of 98

1.18

1.29

2.16e-05

GO:0010467

Gene expression

10 of 207

1.01

1.16

4.07e-07

GO:0009059

Macromolecule biosynthetic process

10 of 215

0.99

1.13

4.07e-07

GO:0044271

Cellular nitrogen compound biosynthetic process

10 of 277

0.88

0.91

2.27e-06

GO:0006351

Transcription, DNA-templated

3 of 26

1.38

0.82

0.0151

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

7 of 52

1.45

2.0

7.39e-07

GO:0019843

rRNA binding

6 of 41

1.49

1.92

3.60e-06

GO:0003899

DNA-directed 5-3 RNA polymerase activity

3 of 5

2.1

1.74

0.00040

GO:0003676

Nucleic acid binding

10 of 470

0.65

0.56

0.00015

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000428

DNA-directed RNA polymerase complex

3 of 5

2.1

2.09

7.10e-05

GO:0015935

Small ribosomal subunit

3 of 6

2.02

2.03

7.97e-05

GO:0005840

Ribosome

7 of 58

1.4

1.98

2.88e-07

GO:0032991

Protein-containing complex

6 of 184

0.84

0.7

0.00074

GO:0005622

Intracellular anatomical structure

9 of 846

0.35

0.27

0.0196

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:87

Mixed, incl. Ribosome, and Regulation of translation

11 of 118

1.29

2.18

5.42e-12

CL:105

Ribosomal protein

7 of 57

1.41

2.04

1.46e-07

CL:305

RNA polymerase

3 of 5

2.1

1.97

0.00013

CL:108

Ribosomal protein

6 of 51

1.39

1.8

2.31e-06

CL:90

Ribosome, and Regulation of translation

8 of 91

1.27

1.75

8.05e-08

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

7 of 56

1.42

2.02

2.53e-07

map03020

RNA polymerase

3 of 5

2.1

1.85

0.00024

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-9635486

Infection with Mycobacterium tuberculosis

3 of 55

1.06

0.59

0.0298

MAP-5663205

Infectious disease

3 of 60

1.02

0.58

0.0298

MAP-1643685

Disease

3 of 61

1.01

0.57

0.0298

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

5 of 45

1.37

1.31

0.00031

GOCC:0022626

Cytosolic ribosome

3 of 11

1.76

1.28

0.0023

GOCC:0044391

Ribosomal subunit

3 of 16

1.59

1.2

0.0024

GOCC:0022627

Cytosolic small ribosomal subunit

2 of 6

1.84

1.0

0.0111

GOCC:0043229

Intracellular organelle

7 of 228

0.81

0.63

0.0023

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

7 of 52

1.45

2.09

2.39e-07

KW-0699

rRNA-binding

6 of 39

1.51

2.09

8.86e-07

KW-0240

DNA-directed RNA polymerase

3 of 5

2.1

1.95

0.00014

KW-0548

Nucleotidyltransferase

3 of 22

1.46

1.03

0.0047

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