STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C475_02488alpha-L-glutamate ligase; COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase). (299 aa)    
Predicted Functional Partners:
C475_02483
Lysine biosynthesis protein LysW.
 
 
 
 0.992
lysZ
Acetylglutamate/acetylaminoadipate kinase; Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis); Belongs to the acetylglutamate kinase family. LysZ subfamily.
 
  
 0.964
lysK-2
Acetyl-lysine deacetylase; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.
 
  
 0.927
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
 
   
 0.898
C475_02513
COG0078 Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
   
 0.812
lysJ
Acetylornithine aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
 
   
 0.806
argG
COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
  
  0.662
argH
COG0165 Argininosuccinate lyase.
     
 0.548
secD
Preprotein translocase subunit SecD; Involved in protein export.
    
 0.500
C475_15088
COG0473 Isocitrate/isopropylmalate dehydrogenase.
    
 0.491
Your Current Organism:
Halosimplex carlsbadense
NCBI taxonomy Id: 797114
Other names: H. carlsbadense 2-9-1, Halosimplex carlsbadense 2-9-1, Halosimplex carlsbadense ATCC BAA-75, Halosimplex carlsbadense JCM 11222, Halosimplex carlsbadense str. 2-9-1, Halosimplex carlsbadense strain 2-9-1
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