STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hisSUnannotated protein; Belongs to the class-II aminoacyl-tRNA synthetase family. (432 aa)    
Predicted Functional Partners:
hisG
Unannotated protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
 
 0.982
ZOD2009_06774
Unannotated protein.
  
 0.970
hisE
Unannotated protein.
  
 
 0.822
eif2g
Unannotated protein; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily.
  
 0.820
ZOD2009_19678
Unannotated protein.
 
 
 0.811
valS
Unannotated protein; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
 
 
 0.784
hisI
Unannotated protein; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
    
 0.778
cysS
Unannotated protein.
  
  
 0.774
thrS-2
Unannotated protein; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
 
 0.746
alaS
Unannotated protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
 
 
 0.741
Your Current Organism:
Haladaptatus paucihalophilus
NCBI taxonomy Id: 797209
Other names: H. paucihalophilus DX253, Haladaptatus paucihalophilus DX253, Haladaptatus paucihalophilus JCM 13897, Haladaptatus paucihalophilus str. DX253, Haladaptatus paucihalophilus strain DX253
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