Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Score
AEH35415.1KEGG: htu:Htur_2313 glycine dehydrogenase (decarboxylating); PFAM: Glycine cleavage system P-protein, N-terminal. (448 aa)    
Predicted Functional Partners:
AEH35416.1
PFAM: Aminotransferase, class V/Cysteine desulfurase; KEGG: htu:Htur_2314 glycine dehydrogenase (decarboxylating).
 0.999
gcvT
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine.
 
 0.999
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
 0.999
AEH38093.1
TIGRFAM: Folate-binding, YgfZ; KEGG: htu:Htur_3469 folate-binding protein YgfZ; PFAM: Glycine cleavage T-protein, N-terminal; Glycine cleavage T-protein, C-terminal barrel.
 
 0.992
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.955
glyA-2
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.955
folD
Bifunctional protein folD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
 
 0.934
AEH35752.1
TIGRFAM: Dihydrolipoamide dehydrogenase; KEGG: nmg:Nmag_1665 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation.
 
 
 0.932
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
 0.917
AEH36031.1
KEGG: hvo:HVO_B0014 sacrosine dehydrogenase/glycine cleavage T-protein; PFAM: FAD dependent oxidoreductase; Glycine cleavage T-protein, N-terminal; Glycine cleavage T-protein, C-terminal barrel.
 
  
 0.906
Your Current Organism:
Halopiger xanaduensis
NCBI taxonomy Id: 797210
Other names: H. xanaduensis SH-6, Halopiger xanaduensis JCM 14033, Halopiger xanaduensis SH-6, Halopiger xanaduensis str. SH-6, Halopiger xanaduensis strain SH-6
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