Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
cobSCobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (255 aa)    
Predicted Functional Partners:
AEH36859.1
KEGG: htu:Htur_2835 GTP:adenosylcobinamide-phosphateguanylyl transferase-like protein.
 
  
  0.994
AEH37791.1
ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; KEGG: htu:Htur_5207 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP.
 
 
 0.984
cobD
Cobalamin biosynthesis protein cbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
   
 0.983
AEH36858.1
UPF0284 protein; TIGRFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative; HAMAP: UPF0284 protein; KEGG: nmg:Nmag_0990 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like, core; Belongs to the UPF0284 family.
 
  
 0.977
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.976
AEH36857.1
L-threonine-O-3-phosphate decarboxylase; KEGG: htu:Htur_2837 aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase, class I/II.
 
   
 0.964
AEH36856.1
KEGG: htu:Htur_2838 adenosylcobinamide hydrolase; PFAM: Adenosylcobinamide amidohydrolase, CbiZ.
 
   
 0.957
AEH36862.1
PFAM: Haloacid dehalogenase-like hydrolase; KEGG: htu:Htur_2832 haloacid dehalogenase domain protein hydrolase.
 
     0.938
AEH35418.1
ATP/cobalamin adenosyltransferase; TIGRFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, PduO-type, N-terminal; KEGG: htu:Htur_2316 ATP/cobalamin adenosyltransferase; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, EutT/PduO type.
    
 0.935
AEH37551.1
precorrin-3B C17-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; KEGG: htu:Htur_0991 precorrin-3B C17-methyltransferase; PFAM: Tetrapyrrole methylase.
 
  
 0.902
Your Current Organism:
Halopiger xanaduensis
NCBI taxonomy Id: 797210
Other names: H. xanaduensis SH-6, Halopiger xanaduensis JCM 14033, Halopiger xanaduensis SH-6, Halopiger xanaduensis str. SH-6, Halopiger xanaduensis strain SH-6
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.