Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH36865.1F420-dependent oxidoreductase, G6PDH family; KEGG: hmu:Hmuk_0326 luciferase-like monooxygenase; TIGRFAM: Glucose-6-phosphate dehydrogenase-related, F420-dependent; PFAM: Luciferase-like, subgroup. (342 aa)    
Predicted Functional Partners:
cofD
LPPG:FO 2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
 
   
 0.716
cofE
F420-0:gamma-glutamyl ligase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives.
 
   
 0.707
cofG
FO synthase subunit 1; Catalyzes the radical-mediated synthesis of 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) from 5-amino-5-(4-hydroxybenzyl)-6-(D- ribitylimino)-5,6-dihydrouracil.
 
  
 0.524
AEH37230.1
Putative F420-dependent enzyme; KEGG: hla:Hlac_0550 pyridoxamine 5'-phosphate oxidase-related FMN-binding; TIGRFAM: F420-binding domain, putative; PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain.
  
     0.434
AEH37113.1
PFAM: Protein of unknown function DUF305; KEGG: srt:Srot_2541 hypothetical protein.
  
     0.425
AEH36864.1
KEGG: htu:Htur_2829 hypothetical protein.
       0.422
AEH38214.1
KEGG: htu:Htur_0730 PPOX class putative F420-dependent enzyme; TIGRFAM: F420-binding domain, putative; PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain.
  
     0.407
Your Current Organism:
Halopiger xanaduensis
NCBI taxonomy Id: 797210
Other names: H. xanaduensis SH-6, Halopiger xanaduensis JCM 14033, Halopiger xanaduensis SH-6, Halopiger xanaduensis str. SH-6, Halopiger xanaduensis strain SH-6
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