STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEH38834.1TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; KEGG: htu:Htur_1986 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase. (584 aa)    
Predicted Functional Partners:
AEH38835.1
TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; KEGG: htu:Htur_1985 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
 
 0.999
AEH37437.1
TIGRFAM: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate; KEGG: nmg:Nmag_2382 pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
 
 0.998
AEH35755.1
TIGRFAM: Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit subgroup x; KEGG: nmg:Nmag_1668 pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; PFAM: Dehydrogenase, E1 component.
    
 0.953
AEH35753.1
Dihydrolipoyllysine-residue acetyltransferase; KEGG: htu:Htur_3595 catalytic domain of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenase acyltransferase, catalytic domain; Biotin/lipoyl attachment; E3 binding.
    
 0.952
AEH37829.1
CoA-binding domain protein; PFAM: CoA-binding; ATP-grasp fold, succinyl-CoA synthetase-type; KEGG: htu:Htur_1637 CoA-binding domain protein.
  
 0.940
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.924
sucC
Succinyl-CoA ligase (ADP-forming) subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
    
 0.924
AEH37011.1
TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; KEGG: htu:Htur_2769 acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding region; Thiamine pyrophosphate enzyme, central region; Thiamine pyrophosphate enzyme, C-terminal TPP-binding.
  
 
 0.919
AEH37012.1
KEGG: htu:Htur_2768 acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT.
  
 
 0.919
AEH38513.1
TIGRFAM: Pyruvate kinase; KEGG: htu:Htur_0844 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, alpha/beta; PEP-utilising enzyme, mobile region; Belongs to the pyruvate kinase family.
  
 
 0.919
Your Current Organism:
Halopiger xanaduensis
NCBI taxonomy Id: 797210
Other names: H. xanaduensis SH-6, Halopiger xanaduensis JCM 14033, Halopiger xanaduensis SH-6, Halopiger xanaduensis str. SH-6, Halopiger xanaduensis strain SH-6
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