| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AHF98405.1 | AHF99847.1 | HALLA_05445 | HALLA_14680 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.828 |
| AHF98405.1 | AHG00627.1 | HALLA_05445 | HALLA_19370 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.920 |
| AHF98405.1 | AHG00749.1 | HALLA_05445 | HALLA_05930 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.924 |
| AHF98405.1 | fen | HALLA_05445 | HALLA_09965 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as [...] | 0.664 |
| AHF98405.1 | rpoD | HALLA_05445 | HALLA_13865 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. | 0.765 |
| AHF98405.1 | rpoH | HALLA_05445 | HALLA_05165 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.663 |
| AHF98405.1 | rpoN | HALLA_05445 | HALLA_13890 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. | 0.707 |
| AHF98405.1 | rpoP | HALLA_05445 | HALLA_10160 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. | 0.658 |
| AHF98405.1 | tbp | HALLA_05445 | HALLA_18870 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcription factor; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. | 0.722 |
| AHF98405.1 | tfe | HALLA_05445 | HALLA_09305 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcription factor; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to [...] | 0.799 |
| AHF99847.1 | AHF98405.1 | HALLA_14680 | HALLA_05445 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.828 |
| AHF99847.1 | AHG00627.1 | HALLA_14680 | HALLA_19370 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.828 |
| AHF99847.1 | AHG00749.1 | HALLA_14680 | HALLA_05930 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.828 |
| AHF99847.1 | fen | HALLA_14680 | HALLA_09965 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as [...] | 0.944 |
| AHF99847.1 | rpoD | HALLA_14680 | HALLA_13865 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. | 0.965 |
| AHF99847.1 | rpoH | HALLA_14680 | HALLA_05165 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. | 0.976 |
| AHF99847.1 | rpoN | HALLA_14680 | HALLA_13890 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. | 0.964 |
| AHF99847.1 | rpoP | HALLA_14680 | HALLA_10160 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit P; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoP/eukaryotic RPC10 RNA polymerase subunit family. | 0.964 |
| AHF99847.1 | tbp | HALLA_14680 | HALLA_18870 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcription factor; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. | 0.954 |
| AHF99847.1 | tfe | HALLA_14680 | HALLA_09305 | Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcription factor; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to [...] | 0.991 |