close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AHF98514.1Replication protein A protects and stabilize the intermediate ssDNA that is generated by the unwinding action of a DNA helicase at the replication fork. In addition, SSBs prevent the formation of secondary structures by single-stranded template DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa)    
Predicted Functional Partners:
AHG00660.1
Hef nuclease; Forms a homodimer; branch structure nuclease; possesses helicase and nuclease activity; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.899
mre11
Metallophosphatase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity; Belongs to the MRE11/RAD32 family.
  
 0.866
pcn
DNA polymerase; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
  
 0.821
AHF98513.1
Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.795
AHF98512.1
Acetoin utilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   0.742
radA
DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
 
 0.734
AHF98424.1
MCM / cell division control protein 21; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MCM family.
  
 0.716
AHF99425.1
MCM / cell division control protein 21; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MCM family.
  
 0.708
AHF99436.1
MCM / cell division control protein 21; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.708
priL
DNA primase; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
  
 0.704
Your Current Organism:
Halostagnicola larsenii
NCBI taxonomy Id: 797299
Other names: H. larsenii XH-48, Halostagnicola larsenii JCM 13463, Halostagnicola larsenii XH-48, Halostagnicola larsenii str. XH-48, Halostagnicola larsenii strain XH-48
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.