| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AHF98665.1 | AHF98666.1 | HALLA_07175 | HALLA_07180 | Signal peptide peptidase SppA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.582 |
| AHF98665.1 | AHF98667.1 | HALLA_07175 | HALLA_07185 | Signal peptide peptidase SppA; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.536 |
| AHF98666.1 | AHF98665.1 | HALLA_07180 | HALLA_07175 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Signal peptide peptidase SppA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.582 |
| AHF98666.1 | AHF98667.1 | HALLA_07180 | HALLA_07185 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.632 |
| AHF98667.1 | AHF98665.1 | HALLA_07185 | HALLA_07175 | ATP binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Signal peptide peptidase SppA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.536 |
| AHF98667.1 | AHF98666.1 | HALLA_07185 | HALLA_07180 | ATP binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.632 |
| AHF98667.1 | AHF99386.1 | HALLA_07185 | HALLA_11435 | ATP binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.547 |
| AHF98667.1 | AHF99415.1 | HALLA_07185 | HALLA_11610 | ATP binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | 0.585 |
| AHF98667.1 | AHG00569.1 | HALLA_07185 | HALLA_19025 | ATP binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Similar to yeast Dim2p protein that is essential for 40S ribosomal subunit; structural studies show binding to 3' end of 16S rRNA in complex with archaeal IF2 alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.467 |
| AHF98667.1 | dphB | HALLA_07185 | HALLA_08355 | ATP binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. | 0.827 |
| AHF98667.1 | fen | HALLA_07185 | HALLA_09965 | ATP binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as [...] | 0.449 |
| AHF98667.1 | fusA | HALLA_07185 | HALLA_05215 | ATP binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | 0.926 |
| AHF98667.1 | rpl23 | HALLA_07185 | HALLA_15480 | ATP binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. | 0.445 |
| AHF98667.1 | rpl4lp | HALLA_07185 | HALLA_15475 | ATP binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. | 0.473 |
| AHF99386.1 | AHF98667.1 | HALLA_11435 | HALLA_07185 | Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.547 |
| AHF99415.1 | AHF98667.1 | HALLA_11610 | HALLA_07185 | Diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | ATP binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.585 |
| AHF99415.1 | AHG00569.1 | HALLA_11610 | HALLA_19025 | Diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Similar to yeast Dim2p protein that is essential for 40S ribosomal subunit; structural studies show binding to 3' end of 16S rRNA in complex with archaeal IF2 alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.554 |
| AHF99415.1 | dphB | HALLA_11610 | HALLA_08355 | Diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Diphthine synthase; S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis. | 0.888 |
| AHF99415.1 | fen | HALLA_11610 | HALLA_09965 | Diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as [...] | 0.428 |
| AHF99415.1 | fusA | HALLA_11610 | HALLA_05215 | Diphthamide biosynthesis protein; Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L- methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2). Belongs to the DPH1/DPH2 family. | Elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. | 0.968 |
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