| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AHF98495.1 | AHF98732.1 | HALLA_06190 | HALLA_07560 | Replication protein A protects and stabilize the intermediate ssDNA that is generated by the unwinding action of a DNA helicase at the replication fork. In addition, SSBs prevent the formation of secondary structures by single-stranded template DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chromosome segregation protein ScpA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.446 |
| AHF98495.1 | fen | HALLA_06190 | HALLA_09965 | Replication protein A protects and stabilize the intermediate ssDNA that is generated by the unwinding action of a DNA helicase at the replication fork. In addition, SSBs prevent the formation of secondary structures by single-stranded template DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as [...] | 0.588 |
| AHF98495.1 | lig | HALLA_06190 | HALLA_12600 | Replication protein A protects and stabilize the intermediate ssDNA that is generated by the unwinding action of a DNA helicase at the replication fork. In addition, SSBs prevent the formation of secondary structures by single-stranded template DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.541 |
| AHF98495.1 | mre11 | HALLA_06190 | HALLA_10475 | Replication protein A protects and stabilize the intermediate ssDNA that is generated by the unwinding action of a DNA helicase at the replication fork. In addition, SSBs prevent the formation of secondary structures by single-stranded template DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Metallophosphatase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity; Belongs to the MRE11/RAD32 family. | 0.865 |
| AHF98495.1 | radA | HALLA_06190 | HALLA_05080 | Replication protein A protects and stabilize the intermediate ssDNA that is generated by the unwinding action of a DNA helicase at the replication fork. In addition, SSBs prevent the formation of secondary structures by single-stranded template DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | 0.696 |
| AHF98495.1 | radB | HALLA_06190 | HALLA_14570 | Replication protein A protects and stabilize the intermediate ssDNA that is generated by the unwinding action of a DNA helicase at the replication fork. In addition, SSBs prevent the formation of secondary structures by single-stranded template DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair protein RadB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. | 0.681 |
| AHF98495.1 | smc | HALLA_06190 | HALLA_07555 | Replication protein A protects and stabilize the intermediate ssDNA that is generated by the unwinding action of a DNA helicase at the replication fork. In addition, SSBs prevent the formation of secondary structures by single-stranded template DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.649 |
| AHF98495.1 | topA | HALLA_06190 | HALLA_10270 | Replication protein A protects and stabilize the intermediate ssDNA that is generated by the unwinding action of a DNA helicase at the replication fork. In addition, SSBs prevent the formation of secondary structures by single-stranded template DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.772 |
| AHF98514.1 | fen | HALLA_06310 | HALLA_09965 | Replication protein A protects and stabilize the intermediate ssDNA that is generated by the unwinding action of a DNA helicase at the replication fork. In addition, SSBs prevent the formation of secondary structures by single-stranded template DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as [...] | 0.683 |
| AHF98514.1 | lig | HALLA_06310 | HALLA_12600 | Replication protein A protects and stabilize the intermediate ssDNA that is generated by the unwinding action of a DNA helicase at the replication fork. In addition, SSBs prevent the formation of secondary structures by single-stranded template DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.541 |
| AHF98514.1 | mre11 | HALLA_06310 | HALLA_10475 | Replication protein A protects and stabilize the intermediate ssDNA that is generated by the unwinding action of a DNA helicase at the replication fork. In addition, SSBs prevent the formation of secondary structures by single-stranded template DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Metallophosphatase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity; Belongs to the MRE11/RAD32 family. | 0.866 |
| AHF98514.1 | radA | HALLA_06310 | HALLA_05080 | Replication protein A protects and stabilize the intermediate ssDNA that is generated by the unwinding action of a DNA helicase at the replication fork. In addition, SSBs prevent the formation of secondary structures by single-stranded template DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. | 0.734 |
| AHF98514.1 | radB | HALLA_06310 | HALLA_14570 | Replication protein A protects and stabilize the intermediate ssDNA that is generated by the unwinding action of a DNA helicase at the replication fork. In addition, SSBs prevent the formation of secondary structures by single-stranded template DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair protein RadB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange. | 0.638 |
| AHF98514.1 | smc | HALLA_06310 | HALLA_07555 | Replication protein A protects and stabilize the intermediate ssDNA that is generated by the unwinding action of a DNA helicase at the replication fork. In addition, SSBs prevent the formation of secondary structures by single-stranded template DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.633 |
| AHF98514.1 | topA | HALLA_06310 | HALLA_10270 | Replication protein A protects and stabilize the intermediate ssDNA that is generated by the unwinding action of a DNA helicase at the replication fork. In addition, SSBs prevent the formation of secondary structures by single-stranded template DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.694 |
| AHF98730.1 | AHF98732.1 | HALLA_07550 | HALLA_07560 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chromosome segregation protein ScpA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.598 |
| AHF98730.1 | smc | HALLA_07550 | HALLA_07555 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.598 |
| AHF98732.1 | AHF98495.1 | HALLA_07560 | HALLA_06190 | Chromosome segregation protein ScpA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Replication protein A protects and stabilize the intermediate ssDNA that is generated by the unwinding action of a DNA helicase at the replication fork. In addition, SSBs prevent the formation of secondary structures by single-stranded template DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.446 |
| AHF98732.1 | AHF98730.1 | HALLA_07560 | HALLA_07550 | Chromosome segregation protein ScpA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.598 |
| AHF98732.1 | smc | HALLA_07560 | HALLA_07555 | Chromosome segregation protein ScpA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. | 0.908 |