STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
secEPreprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (59 aa)    
Predicted Functional Partners:
secY
Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
  
 
 0.952
nusG
Transcription antitermination protein NusG; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
 
  
 0.904
rpl31e
50S ribosomal protein L31; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribosomal protein L31e family.
  
   0.859
rpl44e
50S ribosomal protein L44; Binds to the 23S rRNA.
  
   0.852
rpl32e
50S ribosomal protein L32; Contacts helix 25 of domain III of the 23S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL32 family.
  
   0.842
rpl22
50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
  
   0.816
rpl19e
50S ribosomal protein L19; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.
  
   0.806
rpl18a
50S ribosomal protein LX; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.801
rpl24p
50S ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit.
   
 
 0.796
rpl15e
50S ribosomal protein L15; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL15 family.
   
   0.794
Your Current Organism:
Halostagnicola larsenii
NCBI taxonomy Id: 797299
Other names: H. larsenii XH-48, Halostagnicola larsenii JCM 13463, Halostagnicola larsenii XH-48, Halostagnicola larsenii str. XH-48, Halostagnicola larsenii strain XH-48
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.