| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB15287.1 | AGB15401.1 | Halru_0660 | Halru_0775 | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | Mevalonate pyrophosphate decarboxylase; PFAM: GHMP kinases N terminal domain; TIGRFAM: diphosphomevalonate decarboxylase. | 0.839 |
| AGB15287.1 | AGB15406.1 | Halru_0660 | Halru_0780 | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.927 |
| AGB15287.1 | AGB15741.1 | Halru_0660 | Halru_1124 | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | NADP-dependent hydroxymethylglutaryl-CoA reductase; PFAM: Hydroxymethylglutaryl-coenzyme A reductase; TIGRFAM: 3-hydroxy-3-methylglutaryl Coenzyme A reductase, hydroxymethylglutaryl-CoA reductase (NADP); Belongs to the HMG-CoA reductase family. | 0.721 |
| AGB15287.1 | AGB16337.1 | Halru_0660 | Halru_1736 | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.927 |
| AGB15287.1 | AGB16340.1 | Halru_0660 | Halru_1739 | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | Putative archaeal kinase; Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids. | 0.968 |
| AGB15287.1 | AGB17173.1 | Halru_0660 | Halru_2592 | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.927 |
| AGB15287.1 | fni | Halru_0660 | Halru_0025 | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.908 |
| AGB15287.1 | mvk | Halru_0660 | Halru_1740 | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.645 |
| AGB15401.1 | AGB15287.1 | Halru_0775 | Halru_0660 | Mevalonate pyrophosphate decarboxylase; PFAM: GHMP kinases N terminal domain; TIGRFAM: diphosphomevalonate decarboxylase. | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | 0.839 |
| AGB15401.1 | AGB15406.1 | Halru_0775 | Halru_0780 | Mevalonate pyrophosphate decarboxylase; PFAM: GHMP kinases N terminal domain; TIGRFAM: diphosphomevalonate decarboxylase. | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.450 |
| AGB15401.1 | AGB15741.1 | Halru_0775 | Halru_1124 | Mevalonate pyrophosphate decarboxylase; PFAM: GHMP kinases N terminal domain; TIGRFAM: diphosphomevalonate decarboxylase. | NADP-dependent hydroxymethylglutaryl-CoA reductase; PFAM: Hydroxymethylglutaryl-coenzyme A reductase; TIGRFAM: 3-hydroxy-3-methylglutaryl Coenzyme A reductase, hydroxymethylglutaryl-CoA reductase (NADP); Belongs to the HMG-CoA reductase family. | 0.785 |
| AGB15401.1 | AGB16337.1 | Halru_0775 | Halru_1736 | Mevalonate pyrophosphate decarboxylase; PFAM: GHMP kinases N terminal domain; TIGRFAM: diphosphomevalonate decarboxylase. | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.450 |
| AGB15401.1 | AGB16340.1 | Halru_0775 | Halru_1739 | Mevalonate pyrophosphate decarboxylase; PFAM: GHMP kinases N terminal domain; TIGRFAM: diphosphomevalonate decarboxylase. | Putative archaeal kinase; Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids. | 0.970 |
| AGB15401.1 | AGB17173.1 | Halru_0775 | Halru_2592 | Mevalonate pyrophosphate decarboxylase; PFAM: GHMP kinases N terminal domain; TIGRFAM: diphosphomevalonate decarboxylase. | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.450 |
| AGB15401.1 | fni | Halru_0775 | Halru_0025 | Mevalonate pyrophosphate decarboxylase; PFAM: GHMP kinases N terminal domain; TIGRFAM: diphosphomevalonate decarboxylase. | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.837 |
| AGB15401.1 | mvk | Halru_0775 | Halru_1740 | Mevalonate pyrophosphate decarboxylase; PFAM: GHMP kinases N terminal domain; TIGRFAM: diphosphomevalonate decarboxylase. | Mevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. | 0.995 |
| AGB15406.1 | AGB15287.1 | Halru_0780 | Halru_0660 | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | 0.927 |
| AGB15406.1 | AGB15401.1 | Halru_0780 | Halru_0775 | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Mevalonate pyrophosphate decarboxylase; PFAM: GHMP kinases N terminal domain; TIGRFAM: diphosphomevalonate decarboxylase. | 0.450 |
| AGB15406.1 | AGB15741.1 | Halru_0780 | Halru_1124 | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | NADP-dependent hydroxymethylglutaryl-CoA reductase; PFAM: Hydroxymethylglutaryl-coenzyme A reductase; TIGRFAM: 3-hydroxy-3-methylglutaryl Coenzyme A reductase, hydroxymethylglutaryl-CoA reductase (NADP); Belongs to the HMG-CoA reductase family. | 0.517 |
| AGB15406.1 | AGB16337.1 | Halru_0780 | Halru_1736 | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.916 |