Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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lipALipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (322 aa)    
Predicted Functional Partners:
AGB14821.1
Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme.
 
 
 0.971
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
  
 0.963
AGB14779.1
Lipoate-protein ligase A.
  
 
 0.931
AGB16961.1
PFAM: Biotin/lipoate A/B protein ligase family.
  
 
 0.931
AGB17004.1
Thioredoxin-like protein; PFAM: NifU-like domain.
  
 0.833
AGB17657.1
Thioredoxin-like protein; PFAM: NifU-like domain.
  
 0.833
AGB14817.1
PFAM: MatE; TIGRFAM: putative efflux protein, MATE family.
     
 0.759
AGB14823.1
Dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
 
  
 0.749
AGB17309.1
Vitamin B12-dependent ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
 
      0.686
AGB14820.1
Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component beta subunit; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
  
  
 0.568
Your Current Organism:
Halovivax ruber
NCBI taxonomy Id: 797302
Other names: H. ruber XH-70, Halovivax ruber JCM 13892, Halovivax ruber XH-70, Halovivax ruber str. XH-70, Halovivax ruber strain XH-70
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