| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB15228.1 | queC | Halru_0598 | Halru_0597 | PFAM: Sugar-specific transcriptional regulator TrmB. | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.590 |
| AGB16205.1 | queC | Halru_1598 | Halru_0597 | PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase, subfamily 2. | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.431 |
| crcB | crcB-2 | Halru_3077 | Halru_3078 | Integral membrane protein possibly involved in chromosome condensation; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | Integral membrane protein possibly involved in chromosome condensation; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | 0.900 |
| crcB | queC | Halru_3077 | Halru_0597 | Integral membrane protein possibly involved in chromosome condensation; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.422 |
| crcB-2 | crcB | Halru_3078 | Halru_3077 | Integral membrane protein possibly involved in chromosome condensation; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | Integral membrane protein possibly involved in chromosome condensation; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | 0.900 |
| crcB-2 | queC | Halru_3078 | Halru_0597 | Integral membrane protein possibly involved in chromosome condensation; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.422 |
| dcd | queC | Halru_1159 | Halru_0597 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.476 |
| dcd | tmk | Halru_1159 | Halru_0968 | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase. | 0.670 |
| queC | AGB15228.1 | Halru_0597 | Halru_0598 | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | PFAM: Sugar-specific transcriptional regulator TrmB. | 0.590 |
| queC | AGB16205.1 | Halru_0597 | Halru_1598 | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase, subfamily 2. | 0.431 |
| queC | crcB | Halru_0597 | Halru_3077 | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Integral membrane protein possibly involved in chromosome condensation; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | 0.422 |
| queC | crcB-2 | Halru_0597 | Halru_3078 | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Integral membrane protein possibly involved in chromosome condensation; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. | 0.422 |
| queC | dcd | Halru_0597 | Halru_1159 | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.476 |
| queC | tgtA | Halru_0597 | Halru_0675 | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | tRNA-guanine transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.472 |
| queC | tmk | Halru_0597 | Halru_0968 | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase. | 0.469 |
| tgtA | queC | Halru_0675 | Halru_0597 | tRNA-guanine transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.472 |
| tmk | dcd | Halru_0968 | Halru_1159 | PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.670 |
| tmk | queC | Halru_0968 | Halru_0597 | PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase. | Queuosine biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.469 |