| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB14866.1 | AGB15287.1 | Halru_0220 | Halru_0660 | 3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Rubredoxin-like zinc ribbon domain (DUF35_N); DUF35 OB-fold domain. | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | 0.696 |
| AGB14866.1 | AGB15401.1 | Halru_0220 | Halru_0775 | 3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Rubredoxin-like zinc ribbon domain (DUF35_N); DUF35 OB-fold domain. | Mevalonate pyrophosphate decarboxylase; PFAM: GHMP kinases N terminal domain; TIGRFAM: diphosphomevalonate decarboxylase. | 0.811 |
| AGB14866.1 | AGB15406.1 | Halru_0220 | Halru_0780 | 3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Rubredoxin-like zinc ribbon domain (DUF35_N); DUF35 OB-fold domain. | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.405 |
| AGB14866.1 | AGB15741.1 | Halru_0220 | Halru_1124 | 3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Rubredoxin-like zinc ribbon domain (DUF35_N); DUF35 OB-fold domain. | NADP-dependent hydroxymethylglutaryl-CoA reductase; PFAM: Hydroxymethylglutaryl-coenzyme A reductase; TIGRFAM: 3-hydroxy-3-methylglutaryl Coenzyme A reductase, hydroxymethylglutaryl-CoA reductase (NADP); Belongs to the HMG-CoA reductase family. | 0.985 |
| AGB14866.1 | AGB16290.1 | Halru_0220 | Halru_1684 | 3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Rubredoxin-like zinc ribbon domain (DUF35_N); DUF35 OB-fold domain. | 3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase N terminal; Hydroxymethylglutaryl-coenzyme A synthase C terminal. | 0.979 |
| AGB14866.1 | AGB16337.1 | Halru_0220 | Halru_1736 | 3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Rubredoxin-like zinc ribbon domain (DUF35_N); DUF35 OB-fold domain. | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.405 |
| AGB14866.1 | AGB16650.1 | Halru_0220 | Halru_2058 | 3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Rubredoxin-like zinc ribbon domain (DUF35_N); DUF35 OB-fold domain. | PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III. | 0.835 |
| AGB14866.1 | AGB17173.1 | Halru_0220 | Halru_2592 | 3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Rubredoxin-like zinc ribbon domain (DUF35_N); DUF35 OB-fold domain. | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.405 |
| AGB14866.1 | fni | Halru_0220 | Halru_0025 | 3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Rubredoxin-like zinc ribbon domain (DUF35_N); DUF35 OB-fold domain. | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.401 |
| AGB15287.1 | AGB14866.1 | Halru_0660 | Halru_0220 | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | 3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Rubredoxin-like zinc ribbon domain (DUF35_N); DUF35 OB-fold domain. | 0.696 |
| AGB15287.1 | AGB15401.1 | Halru_0660 | Halru_0775 | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | Mevalonate pyrophosphate decarboxylase; PFAM: GHMP kinases N terminal domain; TIGRFAM: diphosphomevalonate decarboxylase. | 0.772 |
| AGB15287.1 | AGB15406.1 | Halru_0660 | Halru_0780 | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.927 |
| AGB15287.1 | AGB15741.1 | Halru_0660 | Halru_1124 | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | NADP-dependent hydroxymethylglutaryl-CoA reductase; PFAM: Hydroxymethylglutaryl-coenzyme A reductase; TIGRFAM: 3-hydroxy-3-methylglutaryl Coenzyme A reductase, hydroxymethylglutaryl-CoA reductase (NADP); Belongs to the HMG-CoA reductase family. | 0.673 |
| AGB15287.1 | AGB16290.1 | Halru_0660 | Halru_1684 | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | 3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase N terminal; Hydroxymethylglutaryl-coenzyme A synthase C terminal. | 0.694 |
| AGB15287.1 | AGB16337.1 | Halru_0660 | Halru_1736 | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.927 |
| AGB15287.1 | AGB16340.1 | Halru_0660 | Halru_1739 | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | Putative archaeal kinase; Catalyzes the phosphorylation of isopentenyl phosphate (IP) to isopentenyl diphosphate (IPP). Functions in an alternate mevalonate (MVA) pathway leading to IPP, a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids. | 0.930 |
| AGB15287.1 | AGB16650.1 | Halru_0660 | Halru_2058 | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III. | 0.693 |
| AGB15287.1 | AGB17173.1 | Halru_0660 | Halru_2592 | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | Geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. | 0.927 |
| AGB15287.1 | fni | Halru_0660 | Halru_0025 | Isopentenyldiphosphate isomerase; PFAM: NUDIX domain; TIGRFAM: isopentenyl-diphosphate delta-isomerase, type 1. | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.905 |
| AGB15401.1 | AGB14866.1 | Halru_0775 | Halru_0220 | Mevalonate pyrophosphate decarboxylase; PFAM: GHMP kinases N terminal domain; TIGRFAM: diphosphomevalonate decarboxylase. | 3-hydroxy-3-methylglutaryl CoA synthase; PFAM: Rubredoxin-like zinc ribbon domain (DUF35_N); DUF35 OB-fold domain. | 0.811 |