| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB15301.1 | tgtA | Halru_0674 | Halru_0675 | NTP pyrophosphohydrolase; PFAM: NUDIX domain. | tRNA-guanine transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.816 |
| AGB15306.1 | AGB17352.1 | Halru_0679 | Halru_2778 | PFAM: PUA domain; Queuine tRNA-ribosyltransferase; TIGRFAM: uncharacterized domain 2. | Putative membrane-associated Zn-dependent protease; PFAM: Peptidase family M50. | 0.464 |
| AGB15306.1 | tgtA | Halru_0679 | Halru_0675 | PFAM: PUA domain; Queuine tRNA-ribosyltransferase; TIGRFAM: uncharacterized domain 2. | tRNA-guanine transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.720 |
| AGB16397.1 | hisS | Halru_1798 | Halru_0109 | Putative GTPase, probable translation factor; PFAM: GTPase of unknown function; GTPase of unknown function C-terminal; TGS domain. | PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.480 |
| AGB16397.1 | pyrH | Halru_1798 | Halru_2780 | Putative GTPase, probable translation factor; PFAM: GTPase of unknown function; GTPase of unknown function C-terminal; TGS domain. | Uridylate kinase, putative; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.423 |
| AGB16397.1 | tgtA | Halru_1798 | Halru_0675 | Putative GTPase, probable translation factor; PFAM: GTPase of unknown function; GTPase of unknown function C-terminal; TGS domain. | tRNA-guanine transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.578 |
| AGB16397.1 | truB | Halru_1798 | Halru_2068 | Putative GTPase, probable translation factor; PFAM: GTPase of unknown function; GTPase of unknown function C-terminal; TGS domain. | rRNA pseudouridine synthase, putative; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.427 |
| AGB17019.1 | AGB17352.1 | Halru_2437 | Halru_2778 | WD40-like repeat protein; PFAM: PQQ enzyme repeat; PKD domain; CARDB. | Putative membrane-associated Zn-dependent protease; PFAM: Peptidase family M50. | 0.463 |
| AGB17019.1 | hisS | Halru_2437 | Halru_0109 | WD40-like repeat protein; PFAM: PQQ enzyme repeat; PKD domain; CARDB. | PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.475 |
| AGB17019.1 | nadK-2 | Halru_2437 | Halru_1658 | WD40-like repeat protein; PFAM: PQQ enzyme repeat; PKD domain; CARDB. | Inositol monophosphatase/fructose-1,6-bisphosphatase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.599 |
| AGB17019.1 | tgtA | Halru_2437 | Halru_0675 | WD40-like repeat protein; PFAM: PQQ enzyme repeat; PKD domain; CARDB. | tRNA-guanine transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.552 |
| AGB17076.1 | tgtA | Halru_2494 | Halru_0675 | Prefoldin alpha subunit; PFAM: PUA domain; TIGRFAM: uncharacterized domain 2. | tRNA-guanine transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.946 |
| AGB17352.1 | AGB15306.1 | Halru_2778 | Halru_0679 | Putative membrane-associated Zn-dependent protease; PFAM: Peptidase family M50. | PFAM: PUA domain; Queuine tRNA-ribosyltransferase; TIGRFAM: uncharacterized domain 2. | 0.464 |
| AGB17352.1 | AGB17019.1 | Halru_2778 | Halru_2437 | Putative membrane-associated Zn-dependent protease; PFAM: Peptidase family M50. | WD40-like repeat protein; PFAM: PQQ enzyme repeat; PKD domain; CARDB. | 0.463 |
| AGB17352.1 | hisS | Halru_2778 | Halru_0109 | Putative membrane-associated Zn-dependent protease; PFAM: Peptidase family M50. | PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.603 |
| AGB17352.1 | nadK-2 | Halru_2778 | Halru_1658 | Putative membrane-associated Zn-dependent protease; PFAM: Peptidase family M50. | Inositol monophosphatase/fructose-1,6-bisphosphatase family protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.549 |
| AGB17352.1 | pyrH | Halru_2778 | Halru_2780 | Putative membrane-associated Zn-dependent protease; PFAM: Peptidase family M50. | Uridylate kinase, putative; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.964 |
| AGB17352.1 | tgtA | Halru_2778 | Halru_0675 | Putative membrane-associated Zn-dependent protease; PFAM: Peptidase family M50. | tRNA-guanine transglycosylase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. | 0.613 |
| AGB17352.1 | truB | Halru_2778 | Halru_2068 | Putative membrane-associated Zn-dependent protease; PFAM: Peptidase family M50. | rRNA pseudouridine synthase, putative; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. | 0.423 |
| hisS | AGB16397.1 | Halru_0109 | Halru_1798 | PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family. | Putative GTPase, probable translation factor; PFAM: GTPase of unknown function; GTPase of unknown function C-terminal; TGS domain. | 0.480 |