| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB15124.1 | ribK | Halru_0489 | Halru_2255 | PFAM: PUA domain; TIGRFAM: arCOG04150 universal archaeal PUA-domain protein; uncharacterized domain 2. | Transcriptional regulator of a riboflavin/FAD biosynthetic operon; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.465 |
| AGB15124.1 | ribL | Halru_0489 | Halru_0811 | PFAM: PUA domain; TIGRFAM: arCOG04150 universal archaeal PUA-domain protein; uncharacterized domain 2. | Cytidyltransferase-related enzyme; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.499 |
| AGB15438.1 | AGB15439.1 | Halru_0812 | Halru_0813 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box. | 0.568 |
| AGB15438.1 | AGB15440.1 | Halru_0812 | Halru_0814 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | RecJ-like exonuclease with DnaJ-type Zn-finger domain; PFAM: DHH family; OB-fold nucleic acid binding domain. | 0.748 |
| AGB15438.1 | ribK | Halru_0812 | Halru_2255 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | Transcriptional regulator of a riboflavin/FAD biosynthetic operon; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. | 0.597 |
| AGB15438.1 | ribL | Halru_0812 | Halru_0811 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | Cytidyltransferase-related enzyme; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.929 |
| AGB15439.1 | AGB15438.1 | Halru_0813 | Halru_0812 | PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box. | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | 0.568 |
| AGB15439.1 | AGB15440.1 | Halru_0813 | Halru_0814 | PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box. | RecJ-like exonuclease with DnaJ-type Zn-finger domain; PFAM: DHH family; OB-fold nucleic acid binding domain. | 0.459 |
| AGB15439.1 | ribL | Halru_0813 | Halru_0811 | PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box. | Cytidyltransferase-related enzyme; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.566 |
| AGB15440.1 | AGB15438.1 | Halru_0814 | Halru_0812 | RecJ-like exonuclease with DnaJ-type Zn-finger domain; PFAM: DHH family; OB-fold nucleic acid binding domain. | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | 0.748 |
| AGB15440.1 | AGB15439.1 | Halru_0814 | Halru_0813 | RecJ-like exonuclease with DnaJ-type Zn-finger domain; PFAM: DHH family; OB-fold nucleic acid binding domain. | PAS domain S-box; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box. | 0.459 |
| AGB15440.1 | ribL | Halru_0814 | Halru_0811 | RecJ-like exonuclease with DnaJ-type Zn-finger domain; PFAM: DHH family; OB-fold nucleic acid binding domain. | Cytidyltransferase-related enzyme; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.748 |
| AGB15945.1 | ribL | Halru_1332 | Halru_0811 | PFAM: Response regulator receiver domain; HalX domain. | Cytidyltransferase-related enzyme; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.474 |
| AGB16106.1 | AGB16205.1 | Halru_1498 | Halru_1598 | birA, biotin-(acetyl-CoA-carboxylase) ligase; PFAM: HTH domain; Biotin protein ligase C terminal domain; Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region. | PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase, subfamily 2. | 0.465 |
| AGB16106.1 | ribL | Halru_1498 | Halru_0811 | birA, biotin-(acetyl-CoA-carboxylase) ligase; PFAM: HTH domain; Biotin protein ligase C terminal domain; Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region. | Cytidyltransferase-related enzyme; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.547 |
| AGB16179.1 | AGB16205.1 | Halru_1572 | Halru_1598 | 2, 5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase, archaeal. | PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase, subfamily 2. | 0.491 |
| AGB16179.1 | ribH | Halru_1572 | Halru_0808 | 2, 5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase, archaeal. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.951 |
| AGB16179.1 | ribL | Halru_1572 | Halru_0811 | 2, 5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase, archaeal. | Cytidyltransferase-related enzyme; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. | 0.466 |
| AGB16205.1 | AGB16106.1 | Halru_1598 | Halru_1498 | PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase, subfamily 2. | birA, biotin-(acetyl-CoA-carboxylase) ligase; PFAM: HTH domain; Biotin protein ligase C terminal domain; Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region. | 0.465 |
| AGB16205.1 | AGB16179.1 | Halru_1598 | Halru_1572 | PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase, subfamily 2. | 2, 5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase; PFAM: RibD C-terminal domain; TIGRFAM: riboflavin-specific deaminase C-terminal domain; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase, archaeal. | 0.491 |