| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB14706.1 | AGB14805.1 | Halru_0052 | Halru_0153 | Ankyrin repeat-containing protein; PFAM: Ankyrin repeat. | TPR repeat-containing protein; PFAM: Tetratricopeptide repeat. | 0.983 |
| AGB14706.1 | AGB15438.1 | Halru_0052 | Halru_0812 | Ankyrin repeat-containing protein; PFAM: Ankyrin repeat. | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | 0.901 |
| AGB14706.1 | AGB17624.1 | Halru_0052 | Halru_3058 | Ankyrin repeat-containing protein; PFAM: Ankyrin repeat. | Ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.883 |
| AGB14706.1 | pan | Halru_0052 | Halru_0085 | Ankyrin repeat-containing protein; PFAM: Ankyrin repeat. | 26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | 0.838 |
| AGB14706.1 | pan-2 | Halru_0052 | Halru_1171 | Ankyrin repeat-containing protein; PFAM: Ankyrin repeat. | 26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | 0.838 |
| AGB14706.1 | rps3 | Halru_0052 | Halru_1956 | Ankyrin repeat-containing protein; PFAM: Ankyrin repeat. | Ribosomal protein S3, eukaryotic/archaeal type; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. | 0.821 |
| AGB14805.1 | AGB14706.1 | Halru_0153 | Halru_0052 | TPR repeat-containing protein; PFAM: Tetratricopeptide repeat. | Ankyrin repeat-containing protein; PFAM: Ankyrin repeat. | 0.983 |
| AGB14805.1 | AGB15438.1 | Halru_0153 | Halru_0812 | TPR repeat-containing protein; PFAM: Tetratricopeptide repeat. | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | 0.947 |
| AGB14805.1 | AGB17624.1 | Halru_0153 | Halru_3058 | TPR repeat-containing protein; PFAM: Tetratricopeptide repeat. | Ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.806 |
| AGB14805.1 | pan | Halru_0153 | Halru_0085 | TPR repeat-containing protein; PFAM: Tetratricopeptide repeat. | 26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | 0.842 |
| AGB14805.1 | pan-2 | Halru_0153 | Halru_1171 | TPR repeat-containing protein; PFAM: Tetratricopeptide repeat. | 26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | 0.842 |
| AGB14805.1 | rps15 | Halru_0153 | Halru_0828 | TPR repeat-containing protein; PFAM: Tetratricopeptide repeat. | Ribosomal protein S15P/S13E; PFAM: Ribosomal S13/S15 N-terminal domain; Ribosomal protein S15. | 0.569 |
| AGB14805.1 | rps3 | Halru_0153 | Halru_1956 | TPR repeat-containing protein; PFAM: Tetratricopeptide repeat. | Ribosomal protein S3, eukaryotic/archaeal type; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. | 0.407 |
| AGB15438.1 | AGB14706.1 | Halru_0812 | Halru_0052 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | Ankyrin repeat-containing protein; PFAM: Ankyrin repeat. | 0.901 |
| AGB15438.1 | AGB14805.1 | Halru_0812 | Halru_0153 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | TPR repeat-containing protein; PFAM: Tetratricopeptide repeat. | 0.947 |
| AGB15438.1 | AGB15687.1 | Halru_0812 | Halru_1069 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | PFAM: Eukaryotic translation initiation factor 2 alpha subunit; S1 RNA binding domain. | 0.965 |
| AGB15438.1 | AGB17624.1 | Halru_0812 | Halru_3058 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | Ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.935 |
| AGB15438.1 | eif2b | Halru_0812 | Halru_2349 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain protein; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. | 0.959 |
| AGB15438.1 | pan | Halru_0812 | Halru_0085 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | 26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | 0.948 |
| AGB15438.1 | pan-2 | Halru_0812 | Halru_1171 | Putative metal-dependent protease of the PAD1/JAB1 superfamily. | 26S proteasome subunit P45 family; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-2 [...] | 0.948 |