Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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surE5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (260 aa)    
Predicted Functional Partners:
pyrH
Uridylate kinase, putative; Catalyzes the reversible phosphorylation of UMP to UDP.
 
  
 0.942
guaB
Inosine-5''-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
  
 0.937
AGB17306.1
PFAM: IMP dehydrogenase / GMP reductase domain.
 
  
 0.936
AGB17099.1
GMP synthase family protein; PFAM: Glutamine amidotransferase class-I.
 
  
 0.934
guaAB
GMP synthase, glutamine-hydrolyzing, C-terminal domain or B subunit; Catalyzes the synthesis of GMP from XMP.
    
 0.929
AGB15278.1
PFAM: Lyase; Adenylosuccinate lyase C-terminal; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
    
 0.928
AGB15696.1
PRPP-binding protein, adenine/guanine phosphoribosyltransferase; May catalyze a purine salvage reaction, the substrate is unknown.
    
 0.928
tmk
PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase.
    
 0.924
guaAA
GMP synthase, glutamine-hydrolyzing, N-terminal domain or A subunit; Catalyzes the synthesis of GMP from XMP.
    
 0.923
pyrF
Orotidine 5''-phosphate decarboxylase, subfamily 2; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily.
    
 0.923
Your Current Organism:
Halovivax ruber
NCBI taxonomy Id: 797302
Other names: H. ruber XH-70, Halovivax ruber JCM 13892, Halovivax ruber XH-70, Halovivax ruber str. XH-70, Halovivax ruber strain XH-70
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