Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
AGB15719.1Penicillin-binding protein, beta-lactamase class C; PFAM: Beta-lactamase. (463 aa)    
Predicted Functional Partners:
AGB15720.1
PFAM: MatE; TIGRFAM: putative efflux protein, MATE family; manually curated.
 
   
 0.619
AGB17203.1
PFAM: Glycosyl hydrolase family 3 C terminal domain; Glycosyl hydrolase family 3 N terminal domain.
 
  
 0.567
AGB15721.1
Arabinose efflux permease family protein; PFAM: Major Facilitator Superfamily.
     
 0.509
topA
Topoisomerase IA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superco [...]
       0.456
AGB15509.1
Dipeptidyl aminopeptidase/acylaminoacyl peptidase; PFAM: Prolyl oligopeptidase family.
  
     0.455
AGB15204.1
Dipeptidyl aminopeptidase/acylaminoacyl peptidase; PFAM: Prolyl oligopeptidase family; WD40-like Beta Propeller Repeat.
  
     0.440
AGB15152.1
Putative aminopeptidase; PFAM: PA domain; Peptidase family M28.
 
     0.428
AGB17693.1
Dipeptidyl aminopeptidase/acylaminoacyl peptidase; PFAM: Prolyl oligopeptidase family; WD40-like Beta Propeller Repeat.
 
     0.420
AGB16914.1
Dipeptidyl aminopeptidase/acylaminoacyl peptidase; PFAM: Prolyl oligopeptidase family; WD40-like Beta Propeller Repeat.
  
     0.418
AGB15742.1
Putative TIM-barrel fold metal-dependent hydrolase; PFAM: Amidohydrolase family.
 
     0.415
Your Current Organism:
Halovivax ruber
NCBI taxonomy Id: 797302
Other names: H. ruber XH-70, Halovivax ruber JCM 13892, Halovivax ruber XH-70, Halovivax ruber str. XH-70, Halovivax ruber strain XH-70
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