STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AGB15728.1Putative phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain. (231 aa)    
Predicted Functional Partners:
rtcA
RNA 3'-terminal phosphate cyclase; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
  
    0.562
AGB15729.1
Hypothetical protein.
       0.540
rpoL
DNA-directed RNA polymerase, subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
  
    0.527
AGB16298.1
Putative transcriptional regulator; PFAM: Helix-turn-helix.
  
     0.521
AGB17168.1
Hypothetical protein.
  
     0.470
AGB17541.1
Putative membrane protein; PFAM: MgtC family.
  
     0.469
AGB15914.1
PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family.
  
     0.449
AGB16364.1
Hypothetical protein.
  
     0.442
AGB16183.1
PFAM: Helicase conserved C-terminal domain; DEAD/H associated; DEAD/DEAH box helicase.
  
     0.431
AGB15306.1
PFAM: PUA domain; Queuine tRNA-ribosyltransferase; TIGRFAM: uncharacterized domain 2.
  
     0.430
Your Current Organism:
Halovivax ruber
NCBI taxonomy Id: 797302
Other names: H. ruber XH-70, Halovivax ruber JCM 13892, Halovivax ruber XH-70, Halovivax ruber str. XH-70, Halovivax ruber strain XH-70
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.