Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB15775.1Hypothetical protein; PFAM: Helix-turn-helix; Archaeal phosphomethylpyrimidine kinase. (302 aa)    
Predicted Functional Partners:
dcd
Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.
       0.832
AGB15774.1
Methylase involved in ubiquinone/menaquinone biosynthesis; PFAM: Methyltransferase domain.
       0.681
thi4
Thiazole biosynthesis enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur.
 
   
 0.618
fau-1
Protein of unknown function (DUF402); Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.
  
     0.606
AGB15777.1
PFAM: Peptidyl-tRNA hydrolase PTH2; TIGRFAM: peptidyl-tRNA hydrolase.
       0.558
tfe
Transcription initiation factor IIE, alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing [...]
  
     0.539
pfdB
Prefoldin, beta subunit, archaeal; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding.
 
     0.528
AGB15670.1
Phosphate uptake regulator; PFAM: PhoU domain; SpoVT / AbrB like domain.
  
     0.521
AGB17046.1
Putative transcriptional regulator containing an HTH domain fused to a Zn-ribbon.
  
     0.511
AGB16501.1
Hypothetical protein; PFAM: Domain of unknown function (DUF371).
  
     0.505
Your Current Organism:
Halovivax ruber
NCBI taxonomy Id: 797302
Other names: H. ruber XH-70, Halovivax ruber JCM 13892, Halovivax ruber XH-70, Halovivax ruber str. XH-70, Halovivax ruber strain XH-70
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