Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AGB15777.1PFAM: Peptidyl-tRNA hydrolase PTH2; TIGRFAM: peptidyl-tRNA hydrolase. (112 aa)    
Predicted Functional Partners:
dcd
Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP.
       0.815
truD
tRNA pseudouridine synthase, TruD family; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
  
    0.762
AGB15698.1
PFAM: DNA / pantothenate metabolism flavoprotein; Flavoprotein; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase, prokaryotic.
   
 
  0.718
infB
Translation initiation factor aIF-2/yIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
 
  
 0.702
eif6
Translation initiation factor eIF-6, putative; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex.
  
    0.684
AGB16746.1
20S proteasome subunit (alpha or beta); Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.
 
 
   0.644
AGB17468.1
PFAM: SCO1/SenC.
     
 0.643
AGB17572.1
PFAM: SCO1/SenC.
     
 0.643
fen
Flap structure-specific endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair [...]
 
     0.640
psmA
Proteasome endopeptidase complex, archaeal, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
   0.629
Your Current Organism:
Halovivax ruber
NCBI taxonomy Id: 797302
Other names: H. ruber XH-70, Halovivax ruber JCM 13892, Halovivax ruber XH-70, Halovivax ruber str. XH-70, Halovivax ruber strain XH-70
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