| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB15279.1 | AGB15984.1 | Halru_0652 | Halru_1371 | PFAM: AICARFT/IMPCHase bienzyme; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent. | PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | 0.790 |
| AGB15279.1 | AGB16908.1 | Halru_0652 | Halru_2323 | PFAM: AICARFT/IMPCHase bienzyme; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent. | Dihydropteroate synthase; PFAM: Pterin binding enzyme; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: dihydropteroate synthase; folylpolyglutamate synthase/dihydrofolate synthase. | 0.788 |
| AGB15279.1 | AGB17050.1 | Halru_0652 | Halru_2468 | PFAM: AICARFT/IMPCHase bienzyme; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent. | Aminodeoxychorismate synthase, component I, clade 2; PFAM: chorismate binding enzyme; Anthranilate synthase component I, N terminal region; TIGRFAM: aminodeoxychorismate synthase, component I, clade 2. | 0.562 |
| AGB15279.1 | folD | Halru_0652 | Halru_1785 | PFAM: AICARFT/IMPCHase bienzyme; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent. | 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.999 |
| AGB15279.1 | glyA | Halru_0652 | Halru_1783 | PFAM: AICARFT/IMPCHase bienzyme; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.999 |
| AGB15428.1 | AGB15984.1 | Halru_0802 | Halru_1371 | NADH:ubiquinone oxidoreductase 49 kD subunit 7; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit. | PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | 0.821 |
| AGB15428.1 | AGB16908.1 | Halru_0802 | Halru_2323 | NADH:ubiquinone oxidoreductase 49 kD subunit 7; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit. | Dihydropteroate synthase; PFAM: Pterin binding enzyme; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: dihydropteroate synthase; folylpolyglutamate synthase/dihydrofolate synthase. | 0.821 |
| AGB15428.1 | AGB17050.1 | Halru_0802 | Halru_2468 | NADH:ubiquinone oxidoreductase 49 kD subunit 7; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit. | Aminodeoxychorismate synthase, component I, clade 2; PFAM: chorismate binding enzyme; Anthranilate synthase component I, N terminal region; TIGRFAM: aminodeoxychorismate synthase, component I, clade 2. | 0.570 |
| AGB15428.1 | glyA | Halru_0802 | Halru_1783 | NADH:ubiquinone oxidoreductase 49 kD subunit 7; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.616 |
| AGB15983.1 | AGB15984.1 | Halru_1370 | Halru_1371 | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | 0.792 |
| AGB15983.1 | mptE | Halru_1370 | Halru_1372 | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | Uncharacterized Rossmann fold enzyme; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. | 0.721 |
| AGB15984.1 | AGB15279.1 | Halru_1371 | Halru_0652 | PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | PFAM: AICARFT/IMPCHase bienzyme; Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent. | 0.790 |
| AGB15984.1 | AGB15428.1 | Halru_1371 | Halru_0802 | PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | NADH:ubiquinone oxidoreductase 49 kD subunit 7; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit. | 0.821 |
| AGB15984.1 | AGB15983.1 | Halru_1371 | Halru_1370 | PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | 0.792 |
| AGB15984.1 | AGB16707.1 | Halru_1371 | Halru_2116 | PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. | 0.609 |
| AGB15984.1 | AGB16908.1 | Halru_1371 | Halru_2323 | PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | Dihydropteroate synthase; PFAM: Pterin binding enzyme; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: dihydropteroate synthase; folylpolyglutamate synthase/dihydrofolate synthase. | 0.913 |
| AGB15984.1 | AGB17050.1 | Halru_1371 | Halru_2468 | PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | Aminodeoxychorismate synthase, component I, clade 2; PFAM: chorismate binding enzyme; Anthranilate synthase component I, N terminal region; TIGRFAM: aminodeoxychorismate synthase, component I, clade 2. | 0.694 |
| AGB15984.1 | folD | Halru_1371 | Halru_1785 | PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.743 |
| AGB15984.1 | glyA | Halru_1371 | Halru_1783 | PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.755 |
| AGB15984.1 | mptD | Halru_1371 | Halru_2601 | PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family. | 0.924 |