| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB15306.1 | AGB16625.1 | Halru_0679 | Halru_2031 | PFAM: PUA domain; Queuine tRNA-ribosyltransferase; TIGRFAM: uncharacterized domain 2. | Putative transcriptional regulator; PFAM: Helix-turn-helix. | 0.705 |
| AGB15306.1 | AGB17171.1 | Halru_0679 | Halru_2590 | PFAM: PUA domain; Queuine tRNA-ribosyltransferase; TIGRFAM: uncharacterized domain 2. | Putative membrane protein; PFAM: Domain of unknown function (DUF373). | 0.690 |
| AGB15306.1 | mptD | Halru_0679 | Halru_2601 | PFAM: PUA domain; Queuine tRNA-ribosyltransferase; TIGRFAM: uncharacterized domain 2. | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family. | 0.557 |
| AGB15306.1 | mptE | Halru_0679 | Halru_1372 | PFAM: PUA domain; Queuine tRNA-ribosyltransferase; TIGRFAM: uncharacterized domain 2. | Uncharacterized Rossmann fold enzyme; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. | 0.638 |
| AGB15306.1 | tiaS | Halru_0679 | Halru_2032 | PFAM: PUA domain; Queuine tRNA-ribosyltransferase; TIGRFAM: uncharacterized domain 2. | Putative DNA-binding protein containing a Zn-ribbon domain; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.589 |
| AGB15983.1 | AGB15984.1 | Halru_1370 | Halru_1371 | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | 0.792 |
| AGB15983.1 | mptE | Halru_1370 | Halru_1372 | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | Uncharacterized Rossmann fold enzyme; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. | 0.721 |
| AGB15984.1 | AGB15983.1 | Halru_1371 | Halru_1370 | PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | PFAM: SpoU rRNA Methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1. | 0.792 |
| AGB15984.1 | AGB16908.1 | Halru_1371 | Halru_2323 | PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | Dihydropteroate synthase; PFAM: Pterin binding enzyme; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: dihydropteroate synthase; folylpolyglutamate synthase/dihydrofolate synthase. | 0.913 |
| AGB15984.1 | mptA | Halru_1371 | Halru_1192 | PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | TIGR00294 family protein; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. | 0.538 |
| AGB15984.1 | mptD | Halru_1371 | Halru_2601 | PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family. | 0.924 |
| AGB15984.1 | mptE | Halru_1371 | Halru_1372 | PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | Uncharacterized Rossmann fold enzyme; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. | 0.979 |
| AGB16625.1 | AGB15306.1 | Halru_2031 | Halru_0679 | Putative transcriptional regulator; PFAM: Helix-turn-helix. | PFAM: PUA domain; Queuine tRNA-ribosyltransferase; TIGRFAM: uncharacterized domain 2. | 0.705 |
| AGB16625.1 | AGB17076.1 | Halru_2031 | Halru_2494 | Putative transcriptional regulator; PFAM: Helix-turn-helix. | Prefoldin alpha subunit; PFAM: PUA domain; TIGRFAM: uncharacterized domain 2. | 0.536 |
| AGB16625.1 | AGB17171.1 | Halru_2031 | Halru_2590 | Putative transcriptional regulator; PFAM: Helix-turn-helix. | Putative membrane protein; PFAM: Domain of unknown function (DUF373). | 0.453 |
| AGB16625.1 | mptD | Halru_2031 | Halru_2601 | Putative transcriptional regulator; PFAM: Helix-turn-helix. | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family. | 0.709 |
| AGB16625.1 | mptE | Halru_2031 | Halru_1372 | Putative transcriptional regulator; PFAM: Helix-turn-helix. | Uncharacterized Rossmann fold enzyme; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. | 0.609 |
| AGB16625.1 | tiaS | Halru_2031 | Halru_2032 | Putative transcriptional regulator; PFAM: Helix-turn-helix. | Putative DNA-binding protein containing a Zn-ribbon domain; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. | 0.901 |
| AGB16908.1 | AGB15984.1 | Halru_2323 | Halru_1371 | Dihydropteroate synthase; PFAM: Pterin binding enzyme; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: dihydropteroate synthase; folylpolyglutamate synthase/dihydrofolate synthase. | PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase. | 0.913 |
| AGB16908.1 | mptD | Halru_2323 | Halru_2601 | Dihydropteroate synthase; PFAM: Pterin binding enzyme; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: dihydropteroate synthase; folylpolyglutamate synthase/dihydrofolate synthase. | Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family. | 0.924 |