| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGB15755.1 | purA | Halru_1138 | Halru_0752 | PFAM: Asparagine synthase. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.925 |
| AGB15755.1 | purA-2 | Halru_1138 | Halru_3136 | PFAM: Asparagine synthase. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.925 |
| AGB15755.1 | pyrB | Halru_1138 | Halru_1411 | PFAM: Asparagine synthase. | PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase. | 0.932 |
| AGB15755.1 | pyrI | Halru_1138 | Halru_1410 | PFAM: Asparagine synthase. | Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.904 |
| AGB16205.1 | carA | Halru_1598 | Halru_0656 | PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase, subfamily 2. | PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.946 |
| AGB16205.1 | carB | Halru_1598 | Halru_2319 | PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase, subfamily 2. | Carbamoylphosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.955 |
| AGB16205.1 | pyrB | Halru_1598 | Halru_1411 | PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase, subfamily 2. | PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase. | 0.972 |
| AGB16205.1 | pyrC | Halru_1598 | Halru_1599 | PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase, subfamily 2. | Allantoinase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.953 |
| AGB16205.1 | pyrE | Halru_1598 | Halru_2248 | PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase, subfamily 2. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.995 |
| AGB16205.1 | pyrF | Halru_1598 | Halru_2078 | PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase, subfamily 2. | Orotidine 5''-phosphate decarboxylase, subfamily 2; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.946 |
| AGB16205.1 | pyrI | Halru_1598 | Halru_1410 | PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase, subfamily 2. | Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.746 |
| carA | AGB16205.1 | Halru_0656 | Halru_1598 | PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase, subfamily 2. | 0.946 |
| carA | carB | Halru_0656 | Halru_2319 | PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Carbamoylphosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | 0.999 |
| carA | pyrB | Halru_0656 | Halru_1411 | PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase. | 0.999 |
| carA | pyrC | Halru_0656 | Halru_1599 | PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Allantoinase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.994 |
| carA | pyrE | Halru_0656 | Halru_2248 | PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.932 |
| carA | pyrF | Halru_0656 | Halru_2078 | PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Orotidine 5''-phosphate decarboxylase, subfamily 2; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.905 |
| carA | pyrI | Halru_0656 | Halru_1410 | PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | Aspartate carbamoyltransferase, regulatory subunit; Involved in allosteric regulation of aspartate carbamoyltransferase. | 0.965 |
| carB | AGB16205.1 | Halru_2319 | Halru_1598 | Carbamoylphosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase, subfamily 2. | 0.955 |
| carB | carA | Halru_2319 | Halru_0656 | Carbamoylphosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. | PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. | 0.999 |